Triterpene Glycosides from the Seeds of Dolichos lablab

被引:7
|
作者
Yokosuka, Akihito [1 ]
Takayama, Hiroki [1 ]
Mimaki, Yoshihiro [1 ]
机构
[1] Tokyo Univ Pharm & Life Sci, Dept Med Pharmacognosy, Sch Pharm, 1432-1 Horinouchi, Hachioji, Tokyo 1920392, Japan
关键词
triterpene glycoside; Dolichos lablab; Leguminosae; cytotoxic activity; MEDICINAL FOODSTUFFS; SAPONINS;
D O I
10.1248/cpb.c19-00155
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new triterpene glycosides (1 and 2), together with nine known triterpene glycosides (3-11), were isolated from the seeds of Dolichos lablab (Leguminosae). The structures of the new compounds were determined by spectroscopic analysis, including two-dimensional NMR spectroscopy, and chromatographic analysis of the hydrolyzed products. The isolated compounds did not show cytotoxicity against HL-60 human leukemia cells and HepG2 human hepatoma cells at sample concentrations of 20 mu M.
引用
收藏
页码:604 / 608
页数:5
相关论文
共 50 条
  • [1] AMINOPROPYLAMINOALCOHOLS IN THE SEEDS OF DOLICHOS-LABLAB
    HAMANA, K
    NIITSU, M
    SAMEJIMA, K
    MATSUZAKI, S
    PHYTOCHEMISTRY, 1992, 31 (03) : 893 - 894
  • [2] GLOBULINS OF SEEDS OF DOLICHOS LABLAB L
    SAIANOVA, VV
    DOKLADY AKADEMII NAUK SSSR, 1963, 152 (02): : 478 - &
  • [3] CYTOKININS IN IMMATURE SEEDS OF DOLICHOS-LABLAB
    YOKOTA, T
    UEDA, J
    TAKAHASHI, N
    PHYTOCHEMISTRY, 1981, 20 (04) : 683 - 686
  • [4] Saponins from Dolichos lablab seeds with anti-inflammatory activity
    Zhang, Wei
    Li, Fei
    Cheng, Jiaming
    Wang, Yingying
    Zheng, Yinuo
    Li, Huimin
    Lin, Minghao
    Ruan, Jingya
    Zhang, Yi
    Wang, Tao
    BIOORGANIC CHEMISTRY, 2024, 151
  • [5] Purification and characterization of a polyphenol oxidase from the seeds of field bean (Dolichos lablab)
    Paul, B
    Gowda, LR
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2000, 48 (09) : 3839 - 3846
  • [6] Triterpene glycosides from Sophora japonica L seeds
    Gorbacheva, LA
    Grishkovets, VI
    Drozd, GA
    Chirva, VY
    SAPONINS USED IN TRADITIONAL AND MODERN MEDICINE, 1996, 404 : 501 - 504
  • [7] NUTRIENT COMPOSITION AND ANTINUTRITIONAL FACTORS OF DOLICHOS-LABLAB L SEEDS
    DEKA, RK
    SARKAR, CR
    FOOD CHEMISTRY, 1990, 38 (04) : 239 - 246
  • [8] Affinity purification, physicochemical and immunological characterization of a galactose-specific lectin from the seeds of Dolichos lablab (Indian lablab beans)
    Latha, VL
    Rao, RN
    Nadimpalli, SK
    PROTEIN EXPRESSION AND PURIFICATION, 2006, 45 (02) : 296 - 306
  • [9] STUDIES ON LECTINS .56. ISOLATION AND PROPERTIES OF A LECTIN FROM THE SEEDS OF THE INDIAN BEAN OR LABLAB (DOLICHOS-LABLAB L)
    GURAN, A
    TICHA, M
    FILKA, K
    KOCOUREK, J
    BIOCHEMICAL JOURNAL, 1983, 209 (03) : 653 - 657
  • [10] A polyphenol oxidase and galactose specific lectin chimera from field bean (Dolichos lablab) Seeds
    Kanade, Santosh R.
    Gowda, Lalitha R.
    FASEB JOURNAL, 2007, 21 (05): : A633 - A634