Amadori rearrangement of N-glucosides of 6-substituted 3-amino-2-aryl-4(3H)-quinazolinones

被引：0
|
作者：
Saleh, MA
Abdo, MA
AbdelMegeed, MF
ElHiti, GA
机构：
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1996年 / 35卷 / 02期
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Amadori rearrangement of N-glucosides of 6-substituted 3-amino-2-aryl-4(3H)-quinazolinones has been carried out by the condensation of equimolecular amounts of D-glucose and oxalate of 6-substituted 3-amino-2-aryl-4-(3H)-quinazolinones (1a-f) in boiling methanol. These compounds can also be obtained by heating the N-glucosides of 6-substituted 3-amino-2-aryl-4(3H)-quinazolinones (2a-f) in absolute methanol in the presence of dry oxalic acid. The products obtained are characterized by IR, 1(H) NMR, C-13 NMR and mass spectral data and elemental analyses.
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页码：147 / 150
页数：4
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