Anti-Mullerian hormone: a new marker for ovarian function

被引：585
|
作者：
Visser, JA
de Jong, FH
Laven, JSE
Themmen, APN
机构：
[1] Erasmus MC, Dept Internal Med, NL-3000 DR Rotterdam, Netherlands
[2] Erasmus MC, Div Reprod Med, Dept Obstet & Gynaecol, NL-3000 DR Rotterdam, Netherlands
来源：
REPRODUCTION | 2006年 / 131卷 / 01期
关键词：
D O I：
10.1530/rep.1.00529
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Anti-Mullerian hormone (AMH) is a member of the transforming growth factor beta family of growth and differentiation factors. In the ovary, AMH has an inhibitory effect on primordial follicle recruitment as well as on the responsiveness of growing follicles to follicle-stimulating hormone (FSH). The ovary-specific expression pattern in granulosa cells of growing nonselected follicles makes AMH an ideal marker for the size of the ovarian follicle pool. This review summarizes recent findings concerning AMH and its role as a marker for the quantitative aspect of ovarian reserve as well as ovarian dysfunction.
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收藏
页码：1 / 9
页数：9
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