Diabetes and Risk of Hospitalized Fall Injury Among Older Adults

被引:86
|
作者
Yau, Rebecca K. [1 ,2 ]
Strotmeyer, Elsa S. [3 ]
Resnick, Helaine E. [4 ,5 ,6 ]
Sellmeyer, Deborah E. [7 ]
Feingold, Kenneth R. [8 ]
Cauley, Jane A. [3 ]
Vittinghoff, Eric [9 ]
De Rekeneire, Nathalie [10 ]
Harris, Tamara B. [11 ]
Nevitt, Michael C. [9 ]
Cummings, Steven R. [12 ]
Shorr, Ronald I. [13 ,14 ]
Schwartz, Ann V. [9 ]
机构
[1] Ctr Dis Control & Prevent, Council State & Terr Epidemiologists Appl Epidemi, Atlanta, GA 30333 USA
[2] Univ N Carolina, Injury Prevent Res Ctr, Chapel Hill, NC USA
[3] Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA USA
[4] Univ Maryland, Sch Med, Dept Geriatr, Baltimore, MD 21201 USA
[5] Gerontol Res Educ & Training Ctr, Baltimore, MD USA
[6] Resnick Chodorow & Associates, Silver Spring, MD USA
[7] Johns Hopkins Sch Med, Div Endocrinol, Baltimore, MD USA
[8] Univ Calif San Francisco, Dept Med, Div Endocrinol, San Francisco, CA USA
[9] Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA
[10] Yale Univ, Sch Med, Dept Internal Med, Geriatr Sect, New Haven, CT 06510 USA
[11] NIA, Lab Epidemiol, Bethesda, MD 20892 USA
[12] Calif Pacific Med Ctr Res Inst, San Francisco, CA USA
[13] North Florida South Georgia Vet Hlth Syst, Ctr Geriatr Res Educ & Clin, Gainesville, FL USA
[14] Univ Florida, Dept Aging & Geriatr, Gainesville, FL USA
基金
美国国家卫生研究院;
关键词
BODY-COMPOSITION; ELDERLY RESIDENTS; GLYCEMIC CONTROL; FRACTURE RISK; HEALTH ABC; WOMEN; MELLITUS; PREDICTORS; PEOPLE; TYPE-1;
D O I
10.2337/dc13-0429
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVETo determine whether older adults with diabetes are at increased risk of an injurious fall requiring hospitalization.RESEARCH DESIGN AND METHODSThe longitudinal Health, Aging, and Body Composition Study included 3,075 adults aged 70-79 years at baseline. Hospitalizations that included ICD-9-Clinical Modification codes for a fall and an injury were identified. The effect of diabetes with and without insulin use on the rate of first fall-related injury hospitalization was assessed using proportional hazards models.RESULTSAt baseline, 719 participants had diabetes, and 117 of them were using insulin. Of the 293 participants who were hospitalized for a fall-related injury, 71 had diabetes, and 16 were using insulin. Diabetes was associated with a higher rate of injurious fall requiring hospitalization (hazard ratio [HR] 1.48 [95% CI 1.12-1.95]) in models adjusted for age, race, sex, BMI, and education. In those participants using insulin, compared with participants without diabetes, the HR was 3.00 (1.78-5.07). Additional adjustment for potential intermediaries, such as fainting in the past year, standing balance score, cystatin C level, and number of prescription medications, accounted for some of the increased risk associated with diabetes (1.41 [1.05-1.88]) and insulin-treated diabetes (2.24 [1.24-4.03]). Among participants with diabetes, a history of falling, poor standing balance score, and A1C level 8% were risk factors for an injurious fall requiring hospitalization.CONCLUSIONSOlder adults with diabetes, in particular those using insulin, are at greater risk of an injurious fall requiring hospitalization than those without diabetes. Among those with diabetes, poor glycemic control may increase the risk of an injurious fall.
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页码:3985 / 3991
页数:7
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