Microsatellite Instability as an Emerging Biomarker for Checkpoint Inhibitor Response in Advanced Prostate Cancer

被引:3
|
作者
Reichert, Zachery R. [1 ]
Urrutia, Joshua [2 ]
Alumkal, Joshi J. [2 ,3 ,4 ]
机构
[1] Univ Michigan, Dept Internal Med, Rogel Canc Ctr, Ann Arbor, MI 48109 USA
[2] Oregon Hlth & Sci Univ, Knight Canc Inst, 2720 SW Moody Ave,Mailcode KR PROS, Portland, OR 97201 USA
[3] Oregon Hlth & Sci Univ, Dept Med, Portland, OR 97201 USA
[4] Oregon Hlth & Sci Univ, Dept Mol & Med Genet, Portland, OR 97201 USA
关键词
TUMORS;
D O I
10.1001/jamaoncol.2018.5789
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:478 / 479
页数:3
相关论文
共 50 条
  • [41] TUMOR HOMOLOGY WITH SELF AS A BIOMARKER FOR RESPONSE TO CHECKPOINT INHIBITOR THERAPY
    Richard, Guilhem
    Steinberg, Gary
    Ruggiero, Nicole
    Martin, William
    de Groot, Anne
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A110 - A110
  • [42] Overweight as a Favorable Clinical Biomarker for Checkpoint Inhibitor Therapy Response in Recurrent Gynecologic Cancer Patients
    Bartl, Thomas
    Onoprienko, Arina
    Hofstetter, Gerda
    Muellauer, Leonhard
    Poetsch, Nina
    Fuereder, Thorsten
    Kofler, Paul
    Polterauer, Stephan
    Grimm, Christoph
    BIOMOLECULES, 2021, 11 (11)
  • [43] Neoadjuvant Immune Checkpoint Inhibitor Therapy for Patients With Microsatellite Instability-High Colorectal Cancer: Shedding Light on the Future
    Sahin, Ibrahim Halil
    Zhang, Janie
    Saridogan, Turcin
    Gorantla, Vikram
    Rhree, John
    Malhotra, Monica
    Thomas, Roby
    Hsu, Dennis
    Saeed, Anwaar
    JCO ONCOLOGY PRACTICE, 2023, 19 (05) : 251 - +
  • [44] RESPONSE TO IMMUNE CHECKPOINT BLOCKADE IN PATIENTS WITH MICROSATELLITE INSTABLE AND HIGH TUMOR MUTATIONAL BURDEN PROSTATE CANCER
    Lenis, Andrew T.
    Ravichandran, Vignesh
    Hong Truong
    Reisz, Peter
    Nweji, Barbara
    Autio, Karen
    Morris, Michael
    Slovin, Susan
    Vargas, Hebert Alberto
    Laudone, Vincent
    Ehdaie, Behfar
    Reuter, Victor
    Viale, Agnes
    Schultz, Nikolaus
    Gopalan, Anuradha
    Donoghue, Mark
    Stopsack, Konrad
    Solit, David
    Abida, Wassim
    JOURNAL OF UROLOGY, 2021, 206 : E411 - E411
  • [45] Gut microbiota and clinical response to immune checkpoint inhibitor therapy in patients with advanced cancer
    Chang, John Wen-Cheng
    Hsieh, Jia-Juan
    Tsai, Chih-Yu
    Chiu, Horng-Yih
    Lin, Yu-Feng
    Wu, Chiao-En
    Shen, Yung-Chi
    Hou, Ming-Mo
    Chang, Chieh-Ying
    Chen, Jian-An
    Chen, Chyi-Liang
    Chiu, Cheng-Tang
    Yeh, Yuan-Ming
    Chiu, Cheng-Hsun
    BIOMEDICAL JOURNAL, 2024, 47 (05)
  • [46] Lesion-level response to immune checkpoint inhibitor in patients with advanced gastric cancer
    Motoo, Iori
    Ando, Takayuki
    Kajiura, Shinya
    Ogawa, Kohei
    Tsukada, Kenichiro
    Ueda, Akira
    Suzuki, Nobuhiro
    Nakada, Naokatsu
    Nakashima, Koji
    Hosokawa, Ayumu
    Yasuda, Ichiro
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (04)
  • [47] Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability
    Ando, Yuwa
    Yamauchi, Masami
    Suehiro, Yosuke
    Yamaoka, Kenji
    Kosaka, Yumi
    Fuji, Yasutomo
    Uchikawa, Shinsuke
    Kodama, Kenichiro
    Morio, Kei
    Fujino, Hatsue
    Nakahara, Takashi
    Ono, Atsushi
    Murakami, Eisuke
    Kawaoka, Tomokazu
    Takahashi, Shoichi
    Tsuge, Masataka
    Hiramatsu, Akira
    Imamura, Michio
    Chayama, Kazuaki
    Aikata, Hiroshi
    CLINICAL JOURNAL OF GASTROENTEROLOGY, 2020, 13 (05) : 867 - 872
  • [48] Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability
    Yuwa Ando
    Masami Yamauchi
    Yosuke Suehiro
    Kenji Yamaoka
    Yumi Kosaka
    Yasutomo Fuji
    Shinsuke Uchikawa
    Kenichiro Kodama
    Kei Morio
    Hatsue Fujino
    Takashi Nakahara
    Atsushi Ono
    Eisuke Murakami
    Tomokazu Kawaoka
    Shoichi Takahashi
    Masataka Tsuge
    Akira Hiramatsu
    Michio Imamura
    Kazuaki Chayama
    Hiroshi Aikata
    Clinical Journal of Gastroenterology, 2020, 13 : 867 - 872
  • [49] Radiotherapy plus immune checkpoint inhibitor in prostate cancer
    Li, Tianjie
    Qian, Xinye
    Liu, Jinyang
    Xue, Feng
    Luo, Jing
    Yao, Guanqun
    Yan, Jun
    Liu, Xiaodong
    Xiao, Bo
    Li, Jianxing
    FRONTIERS IN ONCOLOGY, 2023, 13
  • [50] Aggressive-Variant Microsatellite-Stable POLE Mutant Prostate Cancer With High Mutation Burden and Durable Response to Immune Checkpoint Inhibitor Therapy
    Lee, Lisa
    Ali, Siraj
    Genega, Elizabeth
    Reed, Dallas
    Sokol, Ethan
    Mathew, Paul
    JCO PRECISION ONCOLOGY, 2018, 2 : 1 - 8