Can the retinal microvasculature offer clues to cardiovascular risk factors in early life?

被引：15

作者：

Li, Ling-Jun ^{[1
]}

Lee, Yung-Seng ^{[2
]}

Wong, Tien-Yin ^{[1
,3
,4
]}

Cheung, Carol Yim-Lui ^{[1
,3
,4
]}

机构：

[1] Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore 168751, Singapore

[2] Natl Univ Singapore, Dept Paediat, Singapore 117548, Singapore

[3] Duke NUS Grad Med Sch, Off Clin Sci, Ctr Quantitat Med, Singapore, Singapore

[4] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Ophthalmol, Singapore 117595, Singapore

来源：

ACTA PAEDIATRICA | 2013年 / 102卷 / 10期

关键词：

Cardiovascular risk factors; Early life; Environmental factors; Retinal microvasculature; Systemic factors; LOW-BIRTH-WEIGHT; VASCULAR CALIBER; BLOOD-PRESSURE; ENDOTHELIAL FUNCTION; PRETERM CHILDREN; VESSEL DIAMETER; CHILDHOOD; ADULTHOOD; ATHEROSCLEROSIS; SIZE;

D O I：

10.1111/apa.12294

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Adulthood cardiovascular diseases (CVD) burdening in adulthood have been suggested to have possible predisposition early in life. We aimed to systematically review the literatures on retinal microvasculature among paediatric population in relation to a range of environmental and systemic changes. Papers with quantitative retinal vascular assessment and epidemiological design were reviewed. Conclusion This review supports the theory that major vascular diseases have pathological predisposition early in life by providing morphological evidence on retinal microcirculation in vivo.

引用

页码：941 / 946

页数：6

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