Monoindole alkaloids from a marine sponge Mycale fibrexilis

被引:21
|
作者
Wang, Ru-Ping [1 ,2 ,3 ]
Lin, Hou-Wen [2 ]
Li, Ling-Zhi [1 ,3 ]
Gao, Pin-Yi [4 ]
Xu, Ying [1 ,2 ,3 ]
Song, Shao-Jiang [1 ,3 ]
机构
[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang 110016, Peoples R China
[2] Second Mil Med Univ, Changzheng Hosp, Dept Pharm, Lab Marine Drugs, Shanghai 200003, Peoples R China
[3] Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China
[4] Shenyang Univ Chem Technol, Coll Chem Engn, Shenyang 110142, Peoples R China
关键词
Marine sponge; Mycale fibrexilis; Alkaloids; Monoindole alkaloids; CHEMICAL-CONSTITUENTS; BROMOINDOLES; DITERPENE;
D O I
10.1016/j.bse.2012.03.016
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this study, eleven monoindol alkaloids (1-11) were obtained from a marine sponge Mycale fibrexilis (order: Poecilosclerida, family: Mycalidae), of which compound 1 is new. Herein, we first report the chemical investigation on M. fibrexilis. The emergence of monoindole alkaloids is less common in the family Mycalidae, which implies that they might be specific chemical constituents for this species. Crown Copyright (C) 2012 Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:210 / 213
页数:4
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