Clinical Evaluation of a Recombinant Adeno-Associated Virus (rAAV) Alpha-1 Antitrypsin (AAT) Gene Therapy Vector

被引:0
|
作者
Chulay, J.
Brantly, M. [1 ]
Wang, L. [2 ]
Mueller, C. [1 ]
Humphries, M. [1 ]
Spencer, L. [1 ]
Rouhani, F. [1 ]
Conlon, T. [1 ]
Spencer, C. [1 ]
Byrne, B. [1 ]
Wilson, J. [2 ]
Flotte, T. [1 ]
机构
[1] Univ Florida, Gainesville, FL 32611 USA
[2] Univ Penn, Philadelphia, PA 19104 USA
关键词
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A2908
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Recombinant adeno-associated virus: clinical application and development as a gene-therapy vector
    Xiao, Ping-Jie
    Lentz, Thomas B.
    Samulski, R. Jude
    THERAPEUTIC DELIVERY, 2012, 3 (07) : 835 - 856
  • [22] Recombinant adeno-associated virus gene therapy for cystic fibrosis and α1-antitrypsin deficiency
    Flotte, TR
    CHEST, 2002, 121 (03) : 98S - 102S
  • [23] Recombinant adeno-associated virus as delivery vector for gene therapy - A review
    Lu, Y
    STEM CELLS AND DEVELOPMENT, 2004, 13 (01) : 133 - 145
  • [24] Functional human alpha 1 antitrypsin secreted from muscle transduced by adeno-associated virus (rAAV1) vector
    Lu, YQ
    Compbell-Yhompason, M
    Li, CW
    Flotte, TR
    Song, SH
    MOLECULAR THERAPY, 2004, 9 : S41 - S42
  • [25] Evaluation of recombinant adeno-associated virus as a gene transfer vector for the retina
    Grant, CA
    Ponnazhagan, S
    Wang, XS
    Srivastava, A
    Li, TS
    CURRENT EYE RESEARCH, 1997, 16 (09) : 949 - 956
  • [26] Recombinant adeno-associated virus (rAAV) vectors for somatic gene therapy: Recent advances and potential clinical applications
    Hallek, M
    Wendtner, CM
    CYTOKINES AND MOLECULAR THERAPY, 1996, 2 (02): : 69 - 79
  • [27] Phase I trial of intramuscular injection of a recombinant adeno-associated virus serotype 2 α1-antitrypsin (AAT) vector in AAT-deficient adults
    Brantly, Mark L.
    Spencer, L. Terry
    Humphries, Margaret
    Conlon, Thomas J.
    Spencer, Carolyn T.
    Poirier, Amy
    Garlington, Wendy
    Baker, Dawn
    Song, Sihong
    Berns, Kenneth I.
    Muzyczka, Nicholas
    Snyder, Richard O.
    Byrne, Barry J.
    Flotte, Terence R.
    HUMAN GENE THERAPY, 2006, 17 (12) : 1177 - 1186
  • [28] Recombinant adeno-associated virus-2 (rAAV) as a vector for gene delivery into vascular cells.
    Gnatenko, D
    Arnold, T
    Zolotukhin, S
    Muzyczka, N
    Bahou, W
    JOURNAL OF INVESTIGATIVE MEDICINE, 1996, 44 (03) : A319 - A319
  • [29] Clinical gene therapy using recombinant adeno-associated virus vectors
    Mueller, C.
    Flotte, T. R.
    GENE THERAPY, 2008, 15 (11) : 858 - 863
  • [30] Recombinant adeno-associated virus 8 vector in gene therapy: Opportunities and challenges
    Zhao, Liyuan
    Yang, Zixuan
    Zheng, Minhui
    Shi, Lei
    Gu, Mengyun
    Liu, Gang
    Miao, Feng
    Chang, Yan
    Huang, Fanghua
    Tang, Naping
    GENES & DISEASES, 2024, 11 (01) : 283 - 293