Biosynthesis and Stability of Coiled-Coil Peptides Containing (2S,4R)-5,5,5-Trifluoroleucine and (2S,4S)-5,5,5-Trifluoroleucine

被引：50
|
作者：
Montclare, Jin Kim [2 ]
Son, Soojin [1 ]
Clark, Ginevra A. [3 ]
Kumar, Krishna [3 ,4 ]
Tirrell, David A. [1 ]
机构：
[1] CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA
[2] Polytech Univ, Suny Downstate Med Ctr, Dept Biochem, Dept Chem & Biol Sci, Brooklyn, NY 11203 USA
[3] Tufts Univ, Dept Chem, Medford, MA 02155 USA
[4] Tufts Univ New England Med Ctr, Ctr Canc, Boston, MA 02110 USA
来源：
CHEMBIOCHEM | 2009年 / 10卷 / 01期
基金：
美国国家科学基金会;
关键词：
biosynthesis; noncanonical amino acids; protein engineering; stereochemical control; thermostability; 4-ALPHA-HELIX BUNDLE PROTEIN; NONCANONICAL AMINO-ACIDS; TRANSFER-RNA SYNTHETASE; ESCHERICHIA-COLI; GENETIC-CODE; ISOLEUCINE; DESIGN; HEXAFLUOROLEUCINE; STABILIZATION; FLUORINE;
D O I：
10.1002/cbic.200800164
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：84 / 86
页数：3
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