Lupus susceptibility gene Pbx1 promotes atherosclerosis via dysfunctional T cells in a mouse model

被引:0
|
作者
Li, Wei [1 ]
Elshikha, Ahmed [1 ]
Teng, Xiangyu [1 ]
Abboud, Georges [1 ]
Brown, Josephine Michelle [1 ]
Choi, Seung-Chul [1 ]
Fredenburg, Kristianna [1 ]
Major, Amy S. [2 ]
Morel, Laurence [1 ]
机构
[1] Univ Florida, Dept Pathol Immunol & Lab Med, Gainesville, FL 32611 USA
[2] Vanderbilt Univ Sch Med, Div Rheumatol & Immunol, Dept Med, Nashville, TN USA
来源
JOURNAL OF IMMUNOLOGY | 2020年 / 204卷 / 01期
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
142.17
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Transcription factor Pbx1 is required for the development of double positive thymic T cells.
    Sanyal, M
    Tung, JW
    Dejbakhsh-Jones, S
    Strober, S
    Herzenberg, LA
    Clear, ML
    BLOOD, 2004, 104 (11) : 759A - 759A
  • [22] Type 1 Interferon Gene Signature Promotes RBC Alloimmunization in a Lupus Mouse Model
    Lee, June Young
    Madany, Emaan
    El Kadi, Najwa
    Pandya, Sumaarg
    Ng, Kessandra
    Yamashita, Michifumi
    Jefferies, Caroline A.
    Gibb, David R.
    FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [23] Integrated multi-omics analysis of PBX1 in mouse adult neural stem- and progenitor cells identifies a transcriptional module that functionally links PBX1 to TCF3/4
    Laub, Vera
    Nan, Elisabeth
    Elias, Lena
    Donaldson, Ian J.
    Bentsen, Mette
    Rusling, Leona A.
    Schupp, Jonathan
    Lun, Jennifer H.
    Plate, Karl H.
    Looso, Mario
    Langer, Julian D.
    Guenther, Stefan
    Bobola, Nicoletta
    Schulte, Dorothea
    NUCLEIC ACIDS RESEARCH, 2024, 52 (20) : 12262 - 12280
  • [24] IRF5 Deficiency Ameliorates Lupus but Promotes Atherosclerosis and Metabolic Dysfunction in a Mouse Model of Lupus-Associated Atherosclerosis
    Watkins, Amanda A.
    Yasuda, Kei
    Wilson, Gabriella E.
    Aprahamian, Tamar
    Xie, Yao
    Maganto-Garcia, Elena
    Shukla, Prachi
    Oberlander, Lillian
    Laskow, Bari
    Menn-Josephy, Hanni
    Wu, Yuanyuan
    Duffau, Pierre
    Fried, Susan K.
    Lichtman, Andrew H.
    Bonegio, Ramon G.
    Rifkin, Ian R.
    JOURNAL OF IMMUNOLOGY, 2015, 194 (04): : 1467 - 1479
  • [25] IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis
    Watkins, A. A.
    Yasuda, K.
    Wilson, G.
    Aprahamian, T.
    Xie, Y.
    Maganto-Garcia, E.
    Shukla, P.
    Oberlander, L.
    Laskow, B.
    Menn-Josephy, H.
    Yu, W.
    Duffau, P.
    Fried, S. K.
    Lichtman, A. H.
    Bonegio, R. G.
    Rifkin, I. R.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2015, 33 (03) : S19 - S19
  • [26] Pbx1 is a co-factor for Cdx-2 in regulating proglucagon gene expression in pancreatic A cells
    Liu, T
    Branch, DR
    Jin, TR
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2006, 249 (1-2) : 140 - 149
  • [27] Poly-L-arginine promotes ferroptosis in asthmatic airway epithelial cells by modulating PBX1/GABARAPL1 axis
    Pan, Min
    Zhang, Ling
    Chang, Shuang
    Jiang, Xueqin
    Shen, Jiapan
    Feng, Xiaoxia
    Xu, Fangzhou
    Zha, Xiaojun
    Chen, Xu
    Fan, Xiaoyun
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 286
  • [28] E2a/Pbx1 oncogene inhibits terminal differentiation but not myeloid potential of pro-T cells
    R P Bourette
    M-F Grasset
    G Mouchiroud
    Oncogene, 2007, 26 : 234 - 247
  • [29] PBX1 promotes the cell proliferation via JAK2/STAT3 signaling in clear cell renal carcinoma
    Wei, Xin
    Yu, Lili
    Li, Yi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 500 (03) : 650 - 657
  • [30] E2a/Pbx1 oncogene inhibits terminal differentiation but not myeloid potential of pro-T cells
    Bourette, R. P.
    Grasset, M-F
    Mouchiroud, G.
    ONCOGENE, 2007, 26 (02) : 234 - 247