Synthesis and Antimicrobial Activity of New Tetrazoles Incorporating Isoindole-1,3-dione Moiety and Their Sugar Derivatives

被引：14

作者：

Abdel-Rahman, Adel A. -H. ^{[1
]}

Ali, Omar M. ^{[1
]}

Abdel-Megeed, Amira A. -S. ^{[1
]}

机构：

[1] Menoufia Univ, Fac Sci, Dept Chem, Shibin Al Kawm, Egypt

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2013年 / 50卷 / 03期

关键词：

C-FURYL GLYCOSIDES; ANTIVIRAL EVALUATION; STREPTOMYCES-RISHIRIENSIS; OXADIAZOLINE DERIVATIVES; LACTONAMYCIN; ANALOGS; NUCLEOSIDES; CHEMISTRY; DESIGN;

D O I：

10.1002/jhet.1119

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New tetrazole derivatives linked to isoindole-1,3-dione were prepared starting from the corresponding nitrile derivatives. The substituted hydrazides, their corresponding sugar hydrazones, and the derived acyclic C-nucleoside analogs were also synthesized. The antimicrobial results indicated that most of the tested compounds exhibited moderate to high activity, whereas few compounds were found to exhibit little or no activity against the tested microorganisms.

引用

页码：484 / 489

页数：6

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