Apoptosis: an innate immune response to virus infection

被引：347
|
作者：
Everett, H [1 ]
McFadden, G
机构：
[1] Univ Western Ontario, John P Robarts Res Inst, London, ON N6G 2V4, Canada
[2] Univ Western Ontario, Dept Microbiol & Immunol, London, ON N6G 2V4, Canada
来源：
TRENDS IN MICROBIOLOGY | 1999年 / 7卷 / 04期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1016/S0966-842X(99)01487-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Viruses can induce apoptosis of infected cells either directly, to assist virus dissemination, or by inadvertently triggering cellular sensors that initiate cell death. Cellular checkpoints that can function as 'alarm bells' to transmit pro-apoptotic signals in response to virus infections include death receptors, protein kinase R, mitochondrial membrane potential, p53 and the endoplasmic reticulum.
引用
收藏
页码：160 / 165
页数：6
相关论文
共 50 条
  • [31] Impact of lymphocyte apoptosis on the innate immune stages of infection
    Javier A. Carrero
    Emil R. Unanue
    [J]. Immunologic Research, 2007, 38 : 333 - 341
  • [32] Autophagy induced by bovine viral diarrhea virus infection counteracts apoptosis and innate immune activation
    Zhou, Yulong
    Ren, Yachao
    Cong, Yanlong
    Mu, Yu
    Yin, Renfu
    Ding, Zhuang
    [J]. ARCHIVES OF VIROLOGY, 2017, 162 (10) : 3103 - 3118
  • [33] Autophagy induced by bovine viral diarrhea virus infection counteracts apoptosis and innate immune activation
    Yulong Zhou
    Yachao Ren
    Yanlong Cong
    Yu Mu
    Renfu Yin
    Zhuang Ding
    [J]. Archives of Virology, 2017, 162 : 3103 - 3118
  • [34] The innate immune response to Trypanosoma cruzi infection
    Kayama, Hisako
    Takeda, Kiyoshi
    [J]. MICROBES AND INFECTION, 2010, 12 (07) : 511 - 517
  • [35] Innate immune response to viral infection of the lungs
    See, Hayley
    Wark, Peter
    [J]. PAEDIATRIC RESPIRATORY REVIEWS, 2008, 9 (04) : 243 - 250
  • [36] The innate immune response to Burkholderia pseudomallei infection
    D'Elia, R.
    Saint, R.
    Cooper, I.
    Clark, G. C.
    Atkins, H. S.
    [J]. IMMUNOLOGY, 2010, 131 : 157 - 157
  • [37] Skin innate immune response to flaviviral infection
    Garcia, Magali
    Wehbe, Michel
    Leveque, Nicolas
    Bodet, Charles
    [J]. EUROPEAN CYTOKINE NETWORK, 2017, 28 (02) : 41 - 51
  • [38] Dengue virus and the host innate immune response
    Uno, Naoko
    Ross, Ted M.
    [J]. EMERGING MICROBES & INFECTIONS, 2018, 7
  • [39] The Innate Immune Response to Mycobacterium tuberculosis Infection
    Ravesloot-Chavez, Marietta M.
    Van Dis, Erik
    Stanley, Sarah A.
    [J]. ANNUAL REVIEW OF IMMUNOLOGY, VOL 39, 2021, 39 : 611 - 637
  • [40] Epigenetic regulation of the innate immune response to infection
    Qian Zhang
    Xuetao Cao
    [J]. Nature Reviews Immunology, 2019, 19 : 417 - 432
12345