Role of laser-induced plasma formation in pulsed cellular microsurgery and micromanipulation

被引：156
|
作者：
Venugopalan, V
Guerra, A
Nahen, K
Vogel, A
机构：
[1] Univ Calif Irvine, Dept Chem Engn & Mat Sci, Irvine, CA 92697 USA
[2] Univ Calif Irvine, Beckman Laser Inst, Laser Microbeam & Med Program, Irvine, CA 92612 USA
[3] Univ Calif Irvine, Ctr Biomed Engn, Irvine, CA 92697 USA
[4] Med Laser Ctr Lubeck, D-23562 Lubeck, Germany
来源：
PHYSICAL REVIEW LETTERS | 2002年 / 88卷 / 07期
关键词：
D O I：
10.1103/PhysRevLett.88.078103
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
We investigate experimentally the physical processes underlying pulsed cellular microsurgery and micro manipulation using nanosecond 532- and 1064-nm laser pulses focused at high numerical aperture. We find that the laser parameters employed for many microirradiation techniques are congruent with those leading to optical breakdown in water. We determine the size and shape of the laser-induced plasma, pressure of the emitted shock wave, and size and energy of the cavitation bubble formed by the expanding plasma. We discuss implications of the results for biophysical microirradiation procedures.
引用
收藏
页码：781031 / 781034
页数：4
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