Near death experiences: Poxvirus regulation of apoptotic death

被引：74
|
作者：
Taylor, JM [1 ]
Barry, M [1 ]
机构：
[1] Univ Alberta, Dept Med Microbiol & Immunol, Edmonton, AB T6G 2S2, Canada
来源：
VIROLOGY | 2006年 / 344卷 / 01期
基金：
加拿大自然科学与工程研究理事会; 加拿大健康研究院;
关键词：
D O I：
10.1016/j.virol.2005.09.032
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Apoptosis, or programmed cell death, plays a critical role in the elimination of virus-infected cells. As a result, a growing number of viruses encode numerous potent anti-apoptotic proteins to counteract apoptosis in an effort to prolong their own survival. This review describes the numerous mechanisms by which poxviruses inhibit apoptosis thereby modulating life and death of the cell. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码：139 / 150
页数：12
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