Proteomic analysis of a fraction enriched in cell envelope proteins of Acinetobacter baumannii

被引：25

作者：

Marti, Sara ^{[1
]}

Sanchez-Cespedes, Javier ^{[1
]}

Oliveira, Eliandre ^{[2
]}

Bellido, David ^{[2
]}

Giralt, Ernest ^{[3
]}

Vila, Jordi ^{[1
]}

机构：

[1] Univ Barcelona, Fac Med, Microbiol Serv, Ctr Diagnost Biomed,Hosp Clin, Barcelona 08036, Spain

[2] Univ Barcelona, Serv Suport Recerca, E-08036 Barcelona, Spain

[3] Univ Barcelona, Diseny Sintesi & Estruct Peptids & Proteines, E-08036 Barcelona, Spain

来源：

PROTEOMICS | 2006年 / 6卷

关键词：

Acinetobacter baumannii; 2-DE; Cell envelope proteins;

D O I：

10.1002/pmic.200500323

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Acinetobacter baumannii is a multiresistant opportunistic nosocomial pathogen. A protein fraction was purified and analyzed by 2-DE. Twenty-nine major protein spots were selected for protein identification using trypsin digestion and MS analysis. As the A. baumannii genome has not yet been described, protein identification was performed by homology with other Acinetobacter species in the NCBi database. We identified ribosomal proteins, chaperones, elongation factors and outer membrane proteins (Omp), such as OmpA and the 33-36-kDa OMP. Proteomic analysis of A. baumannii provides a platform for further studies in antimicrobial resistance.

引用

页码：S82 / S87

页数：6

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