Docetaxel/cisplatin.: A palliative therapy concept in advanced gastric cancer

被引：0
|
作者：
Ridwelski, K [1 ]
Gebauer, T [1 ]
Fahlke, J [1 ]
Kröning, H [1 ]
Kettner, E [1 ]
Lippert, H [1 ]
机构：
[1] Otto Von Guericke Univ, Hosp Surg, Magdeburg, Germany
来源：
3RD INTERNATIONAL GASTRIC CANCER CONGRESS | 1999年
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Between 1/97 to 10/98 43 patients (pts.)- 30 male and 13 female - with advanced or metastatic gastric cancer (median age of 62.4 (39-75) years) were enrolled in our study. The study finished 39 pts. according to protocol. After application from Docetaxel 75 mg/sqm and Cisplatin 75 mg/sqm we saw 4 CR (10,3%), 12 PR (30,8%), 1 MR (2,5%), 10 SD (25,5%) und 12 P (30,8%). The ORR was 17/39 (43.6%). The median survival time was 12.5 months and the median time to progression 5,8 months. These results show, that the combination of Docetaxel and Cisplatin is a high effective polychemotherapy regarding RR and median survival time. The protocoll could also be proofen as a neoadjuvant concept.
引用
收藏
页码：773 / 777
页数：5
相关论文
共 50 条
  • [41] Neoadjuvant Docetaxel, Capecitabine and Cisplatin (DXP) in Patients with Unresectable Locally Advanced or Metastatic Gastric Cancer
    Sym, Sun Jin
    Chang, Heung Moon
    Ryu, Min-Hee
    Lee, Jae-Lyun
    Kim, Tae Won
    Yook, Jeong Hwan
    Oh, Sung Tae
    Kim, Byung Sik
    Kang, Yoon-Koo
    ANNALS OF SURGICAL ONCOLOGY, 2010, 17 (04) : 1024 - 1032
  • [42] The role of palliative radiation therapy in symptomatic locally advanced gastric cancer
    Tey, Jeremy
    Back, Michael F.
    Shakespeare, Thomas P.
    Mukherjee, Rahul K.
    Lu, Jiade J.
    Lee, Khai Mun
    Wong, Lea Choung
    Leong, Cheng Nang
    Zhu, Ming
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 67 (02): : 385 - 388
  • [43] Proceedings in the palliative treatment of advanced gastric cancer including multimodal therapy
    Stainert, Ralf
    Gastinger, Ingo
    Meyer, Frank
    Ptok, Henry
    Ridwelski, Karsten
    Bruns, Christiane
    Lippert, Hans
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [44] Palliative therapy in gastric cancer
    Lordick, F.
    ONKOLOGIE, 2010, 33 : 100 - 100
  • [45] Palliative gastrectomy for advanced gastric cancer
    Hanazaki, K
    Sodeyama, H
    Mochizuki, Y
    Igarashi, J
    Yokoyama, S
    Sode, Y
    Wakabayashi, M
    Kawamura, N
    Miyazaki, T
    HEPATO-GASTROENTEROLOGY, 2001, 48 (37) : 285 - 289
  • [46] Palliative chemotherapy for advanced gastric cancer
    Wöhrer, SS
    Raderer, A
    Hejna, A
    ANNALS OF ONCOLOGY, 2004, 15 (11) : 1585 - 1595
  • [47] Palliative care for advanced gastric cancer
    Harada, Kazuto
    Zhao, Meina
    Shanbhag, Namita
    Baba, Hideo
    Ajani, Jaffer A.
    EXPERT REVIEW OF ANTICANCER THERAPY, 2020, 20 (07) : 575 - 580
  • [48] Docetaxel, cisplatin, and fluorouracil;: Docetaxel and cisplatin;: and epirubicin, cisplatin, and fluorouracil as systemic treatment for advanced gastric carcinoma:: A randomized phase II trial of the Swiss Group for Clinical Cancer Research
    Roth, Arnaud D.
    Fazio, Nicola
    Stupp, Roger
    Falk, Stephen
    Bernhard, Juerg
    Saletti, Piercarlo
    Koeberle, Dieter
    Borner, Markus M.
    Rufibach, Kaspar
    Maibach, Rudolf
    Wernli, Martin
    Leslie, Martin
    Glynne-Jones, Robert
    Widmer, Lukas
    Seymour, Matthew
    de Braud, Filippo
    JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (22) : 3217 - 3223
  • [49] Capecitabine and docetaxel for advanced gastric cancer.
    Thuss-Patience, P. C.
    Kretzschmar, A.
    Dogan, Y.
    Blau, I.
    Pink, D.
    Lebedinzew, B.
    Micheel, S.
    Dörken, B.
    Reichardt, P.
    JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (18) : 195S - 195S
  • [50] Docetaxel in second line in advanced gastric cancer
    Kheira, Rekai
    Khadidja, Belkharoubi
    Larbaoui, Blaha
    ANNALS OF ONCOLOGY, 2017, 28
12345