Synthesizing Species Trees from Unrooted Gene Trees: A Parameterized Approach

被引:3
|
作者
Moon, Jucheol [1 ]
Eulenstein, Oliver [1 ]
机构
[1] Iowa State Univ, Dept Comp Sci, Ames, IA 50010 USA
基金
美国国家科学基金会;
关键词
Guidance Tree based Unrooted Tree Fill-in; Guidance Tree based Tree Rooting; Pareto for Clusters; Strict Consensus Approach; Gene Duplication; PHYLOGENY;
D O I
10.1145/3107411.3107450
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Synthesizing species trees from a collection of smaller gene trees is a widely used approach for inferring credible species tree estimates. While corresponding computational problems are typically NP-hard, several of these problems have been effectively addressed by using the parameterized Strict Consensus Approach. This approach is limited to gene trees that are rooted. In practice, however, most gene trees are unrooted, and it is often difficult, if not impossible, to identify accurate rootings. Here, we address this stringent limitation by proposing efficient algorithms that adopt the parameterized Strict Consensus Approach to handle unrooted gene trees. Finally, we demonstrate the performance of our algorithms in a comparative study using empirical and simulated data sets.
引用
收藏
页码:253 / 262
页数:10
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