New method for the calculation of cerebral blood flow in near-infrared spectroscopy

被引：0

作者：

Lee, TY ^{[1
]}

Gora, F ^{[1
]}

Elwell, C ^{[1
]}

Smith, M ^{[1
]}

Springett, R ^{[1
]}

Gharavi, J ^{[1
]}

Goldstone, J ^{[1
]}

Delpy, D ^{[1
]}

机构：

[1] St Josephs Hlth Ctr, Lawson Res Inst, Imaging Div, London, ON, Canada

来源：

PROCEEDINGS OF INTER-INSTITUTE WORKSHOP ON IN VIVO OPTICAL IMAGING AT THE NIH | 2000年

关键词：

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The method uses linear systems techniques to model the tissue concentration of a near-infrared chromophore following an abrupt change in the arterial concentration. A robust deconvolution algorithm was developed to derive the impulse residue function (IRF) of the cerebral circulation from the arterial and tissue concentration vs time data measured with near-infrared spectroscopy. The height of the derived IRF is cerebral blood flow (CBF) in absolute physiological units. Experimental studies in human volunteers shows that the precision of CBF measurements with the method is about 12%. Cerebrovascular reactivity towards arterial carbon dioxide tension was also demonstrated in piglets.

引用

页码：81 / 88

页数：8

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