Highly efficient divergent synthesis of dendrimers via metal-free "click" chemistry

被引：15

作者：

Gonzaga, Ferdinand ^{[1
]}

Sadowski, Lukas P. ^{[1
]}

Rambarran, Talena ^{[1
]}

Grande, John ^{[1
]}

Adronov, Alex ^{[1
]}

Brook, Michael A. ^{[1
]}

机构：

[1] McMaster Univ, Dept Chem & Chem Biol, W Hamilton, ON L8S 4M1, Canada

来源：

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY | 2013年 / 51卷 / 06期

基金：

加拿大自然科学与工程研究理事会;

关键词：

alkynes; azides; click chemistry; dendrimers; metal-free; monomers; synthesis; THIOL-ENE; CYCLOADDITION; MACROMOLECULES; CATALYSIS; POLYMERS; DESIGN; AZIDES;

D O I：

10.1002/pola.26511

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A new synthetic strategy to prepare dendrimers using a single, inexpensive monomer is described. Divergent growth relies on a highly efficient, metal-free Click cycloaddition of azides to alkynes. Functional dendrimers are obtained with minimal purification in high yields, with no by-product but a water soluble salt, and the excess of monomer used can be recycled at each stage of the iterative synthesis. © 2012 Wiley Periodicals, Inc.

引用

页码：1272 / 1277

页数：6

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