Toward live-cell imaging of dopamine neurotransmission with fluorescent neurotransmitter analogues

被引：3
|
作者：
Lin, Hui-Jen [1 ,2 ]
Lu, Hsueh-Han [1 ,2 ]
Liu, Kuan-Miao [3 ]
Chau, Chi-Min [3 ]
Hsieh, You-Zung [1 ,2 ]
Li, Yaw-Kuen [1 ,2 ]
Liau, Ian [1 ,2 ]
机构：
[1] Natl Chiao Tung Univ, Dept Appl Chem, Hsinchu 30010, Taiwan
[2] Natl Chiao Tung Univ, Inst Mol Sci, Hsinchu 30010, Taiwan
[3] Chung Shan Med Univ, Sch Med Appl Chem, Taichung 40201, Taiwan
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 74期
关键词：
SK-N-SH; SEROTONIN TRANSPORTER; PC12; CELLS; IN-VIVO; BRAIN; EXPRESSION; RELEASE; INHIBITORS;
D O I：
10.1039/c5cc03050a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report a novel 'fluorescent dopamine' that possesses essential features of natural dopamine. Our method is simple and is readily extended to monoamine neurotransmitters such as L-norepinephrine, serotonin and GABA, providing a more practical approach. Because of its compatibility with sensitive fluorescent measurements, we envisage that our approach will have a broad range of applications in neural research.
引用
收藏
页码：14080 / 14083
页数：4
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