Characteristic Symptoms in Women with Ischemic Heart Disease

被引:3
|
作者
Maas, Angela H. E. M. [1 ]
机构
[1] Radboud Univ Nijmegen, Med Ctr, Dept Cardiol, Geert Grootepl Zuid 10,Route 616, NL-6525 GA Nijmegen, Netherlands
关键词
Atherosclerosis; Coronary spasm; Ischemic heart disease; Microvascular dysfunction; Women; CORONARY MICROVASCULAR DYSFUNCTION; ARTERY-DISEASE; SEX-DIFFERENCES; CLINICAL-OUTCOMES; STABLE ANGINA; CHEST-PAIN; MEN; ATHEROSCLEROSIS; ANGIOGRAPHY; PREVALENCE;
D O I
10.1007/s12170-019-0611-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of ReviewAdvances in coronary imaging techniques have revealed that there are important sex differences in the pattern of ischemic heart disease. In this review, we aim to summarize our current knowledge and focus on the relation between a distinct symptom presentation in women and their underlying type of coronary artery disease.Recent FindingsWomen in the age group 40-70years more often have non-obstructive coronary artery disease (CAD) and coronary vasomotor disorders compared with the traditional obstructive CAD as seen in men. These differences in pathophysiology translate into another symptom presentation which we should rather call characteristic than atypical. Women at risk for coronary vasomotor disorders often have co-morbidities and an enhanced pro-inflammatory state, which leads the way to the appropriate diagnosis. Progress has been made with invasive testing to better discriminate between coronary spasm and microvascular dysfunction. Treatment options are still limited and often disappointing for this heterogeneous patient population.SummarySex differences in ischemic heart disease truly exist and have been clearly defined over the past years. We should therefore approach female patients according to this acquired knowledge. The challenge for the coming years will be a more tailored diagnostic and therapeutic approach for symptomatic women at middle-age.
引用
收藏
页数:5
相关论文
共 50 条
  • [31] Managing Ischemic Heart Disease in Women: Role of a Women’s Heart Center
    Abha Khandelwal
    May Bakir
    Meghan Bezaire
    Briana Costello
    Joanne Michelle D. Gomez
    Valerie Hoover
    Noreen T. Nazir
    Katherine Nichols
    Amy Reisenberg
    Anupama Rao
    Rupa Sanghani
    Melissa Tracy
    Annabelle Santos Volgman
    Current Atherosclerosis Reports, 2021, 23
  • [32] Managing Ischemic Heart Disease in Women: Role of a Women's Heart Center
    Khandelwal, Abha
    Bakir, May
    Bezaire, Meghan
    Costello, Briana
    Gomez, Joanne Michelle D.
    Hoover, Valerie
    Nazir, Noreen T.
    Nichols, Katherine
    Reisenberg, Amy
    Rao, Anupama
    Sanghani, Rupa
    Tracy, Melissa
    Volgman, Annabelle Santos
    CURRENT ATHEROSCLEROSIS REPORTS, 2021, 23 (10)
  • [33] Depressive symptoms in women and men with heart disease
    Stern, SL
    Engebretson, TO
    Fish, A
    Alonzo, AA
    Emery, CF
    Reynolds, NR
    DuJardin, JP
    Larry, JA
    Homan, J
    Frid, DJ
    PSYCHOSOMATIC MEDICINE, 1997, 59 (01): : 87 - 87
  • [34] Heart disease in women: I: pathophysiology and symptoms
    不详
    EUROPEAN HEART JOURNAL, 2012, 33 (07) : 808 - +
  • [35] The association between depressive symptoms and ischemic heart disease in postmenopausal women: a cross-sectional study
    Yuan, Yanyan
    Chen, Gang
    FRONTIERS IN PSYCHOLOGY, 2025, 16
  • [36] Elevated high-density lipoprotein cholesterol and adverse outcomes in women with symptoms of ischemic heart disease
    Ranasinghe, Sachini
    Cui, Yujie
    Muhyieddeen, Amer
    Obrutu, Okezi
    Wei, Janet
    Gulati, Martha
    Bittner, Vera
    Reis, Steven
    Handberg, Eileen
    Pepine, Carl J.
    Merz, C. Noel Bairey
    AMERICAN HEART JOURNAL PLUS: CARDIOLOGY RESEARCH AND PRACTICE, 2024, 40
  • [37] CHARACTERISTIC LABILITY OF CLOTTING AND AUTONOMIC VARIABLES IN PATIENTS WITH ISCHEMIC HEART DISEASE
    SCHNEIDE.RA
    HAMPTON, JW
    COSTILOE, JP
    WOLF, S
    CIRCULATION, 1967, 36 (4S2) : I231 - &
  • [38] Gender Disparities in CAD: Women and Ischemic Heart Disease
    Davies, Rhian E.
    Rier, Jeremy D.
    CURRENT ATHEROSCLEROSIS REPORTS, 2018, 20 (10)
  • [39] Ischemic Heart Disease and Women: More Answers Are Needed
    Escobar, Carlos
    Barrios, Vivencio
    REVISTA ESPANOLA DE CARDIOLOGIA, 2012, 65 (11): : 1066 - 1066
  • [40] ISCHEMIC HEART-DISEASE IN YOUNG-WOMEN
    STEWART, IMG
    BRITISH MEDICAL JOURNAL, 1974, 4 (5945): : 653 - 653