A novel silk fibroin scaffolds with oriented multichannels

被引：13
|
作者：
Zhang, Qiang [1 ]
Li, Mingzhong [2 ]
Xu, Weilin [1 ]
Li, Jianqiang [1 ]
Yan, Shuqin [1 ]
机构：
[1] Wuhan Text Univ, Coll Text Sci & Engn, Wuhan 430073, Peoples R China
[2] Soochow Univ, Coll Text & Clothing Engn, Natl Engn Lab Modern Silk, Suzhou 215123, Peoples R China
来源：
MATERIALS LETTERS | 2013年 / 105卷
关键词：
Silk fibroin; Porous materials; Biomaterials; Structural; Oriented channels; SPINAL-CORD; GROWTH;
D O I：
10.1016/j.matlet.2013.04.049
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Silk fibroin (SF) scaffold with uniaxial channels was prepared by directional temperature field freezing technique. The scaffold morphology was observed by scanning electron microscopy and structures of the scaffold were examined by Fourier Transform Infrared (FTIR) Spectroscopy and X-ray diffractometry (XRD) analysis. The results indicated that beta-sheet content of the scaffolds with oriented channels was more than that of control group. The directional growth of ice crystal could shear and draft to the silk fibroin molecule segments, which resulted in the new crystal nucleus formation in new zone and increase of beta-sheet component. Dependent on this approach, the new oriented multichannel scaffolds were fabricated. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码：8 / 11
页数：4
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