The role of radiotherapy in the overall treatment of melanoma

被引：10
|
作者：
Forschner, Andrea [1 ]
Heinrich, Vanessa [2 ]
Pflugfelder, Annette [1 ]
Meier, Friedegund [1 ]
Garbe, Claus [1 ]
机构：
[1] Univ Tubingen Hosp, Dept Dermatol, D-72076 Tubingen, Germany
[2] Univ Tubingen Hosp, Dept Radiooncol, D-72076 Tubingen, Germany
来源：
CLINICS IN DERMATOLOGY | 2013年 / 31卷 / 03期
关键词：
METASTATIC MALIGNANT-MELANOMA; MULTICENTER RANDOMIZED-TRIAL; GAMMA-KNIFE RADIOSURGERY; WHOLE-BRAIN RADIOTHERAPY; BODY RADIATION-THERAPY; CUTANEOUS MELANOMA; MUCOSAL MELANOMA; PROGNOSTIC-FACTORS; LENTIGO MALIGNA; LOCAL-CONTROL;
D O I：
10.1016/j.clindermatol.2012.08.009
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Radiotherapy has become an effective treatment in the management of melanoma patients. It has its place beneath surgical treatment options in a tumor entity that has only limited response to systemic medical therapies. New therapies, such as ipilimumab and vemurafenib, may prolong survival for several months but will cure only a few patients. Radiotherapy will still be required in adjuvant settings to reduce the local recurrence rate and in palliative situations, particularly in brain and bone metastasis. We review several indications for radiotherapy in the management of malignant melanoma with an effect on the guidelines in our clinical practice. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码：282 / 289
页数：8
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