Nutritional Consideration in Celiac Disease and Nonceliac Gluten Sensitivity

被引:21
|
作者
Naik, Rishi D. [1 ]
Seidner, Douglas L. [1 ]
Adams, Dawn Wiese [1 ]
机构
[1] Vanderbilt Univ, Div Gastroenterol Hepatol & Nutr, Ctr Nutr, Med Ctr, 1211 21st Ave South,Suite 514, Nashville, TN 37232 USA
关键词
Celiac; Nonceliac gluten sensitivity; Gluten; Nutritional deficiencies; Gluten-free diet; Drug development; BONE-MINERAL DENSITY; IRON-DEFICIENCY ANEMIA; FREE DIET; LARAZOTIDE ACETATE; VITAMIN-B-12; DEFICIENCY; WHEAT-SENSITIVITY; COPPER DEFICIENCY; BODY-COMPOSITION; SERUM-ZINC; IN-VITRO;
D O I
10.1016/j.gtc.2017.09.006
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Celiac disease is an autoimmune disorder due to the inflammatory response to gluten in genetically predisposed individuals. It causes an enteropathy associated with several nutritional complications. Strict compliance to a gluten-free diet (GFD) is the current primary therapy. Nonceliac gluten sensitivity (NCGS) is a condition in which gluten ingestion leads to systemic symptoms but is not associated with small bowel atrophy or abnormal celiac serologies. A GFD heals celiac disease enteropathy and improves symptoms in NCGS. However, a long-term GFD can be associated with nutritional deficiencies and requires monitoring and guidance.
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页码:139 / +
页数:17
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