Structural synaptic plasticity across sleep and wake

被引:9
|
作者
Bellesi, Michele [1 ]
de Vivo, Luisa [1 ]
机构
[1] Univ Bristol, Sch Physiol Pharmacol & Neurosci, Biomed Sci Bldg,Univ Walk, Bristol BS8 1TD, Avon, England
来源
基金
英国惠康基金;
关键词
LONG-TERM POTENTIATION; DENDRITIC SPINES; ELECTRON-MICROSCOPY; RAT HIPPOCAMPUS; SYNAPSES; SYNAPTOGENESIS; DYNAMICS; MEMORY; HOMEOSTASIS; AMPA;
D O I
10.1016/j.cophys.2019.12.007
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Sleep-dependent synaptic plasticity is crucial for optimal cognition. However, establishing the direction of synaptic plasticity during sleep has been particularly challenging since data in support of both synaptic potentiation and depotentiation have been reported. This review focuses on structural synaptic plasticity across sleep and wake and summarizes recent developments in the use of 3-dimensional electron microscopy as applied to this field.
引用
收藏
页码:74 / 81
页数:8
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