PRECLINICAL PHARMACOKINETICS OF NATURAL ANTIBIOTIC NEGAMYCIN AND PREDICTION OF ITS PHARMACOKINETICS IN HUMAN

被引:0
|
作者
Guo, Jian [1 ]
Miele, Eric [2 ]
Luzietti, Ricardo A. [1 ]
Walsky, Robert L. [1 ]
机构
[1] AstraZenea, Dept Drug Metab & Pharmacokinet, Waltham, MA USA
[2] AstraZenea, Discovery Sci, Waltham, MA USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
P381
引用
收藏
页码:218 / 218
页数:1
相关论文
共 50 条
  • [1] Pharmacokinetics of the natural antibiotic negamycin
    Guo, Jian
    Miele, Eric W.
    Chen, April
    Luzietti, Ricardo A.
    Zambrowski, Mark
    Walsky, Robert L.
    Buurman, Ed T.
    XENOBIOTICA, 2015, 45 (07) : 625 - 633
  • [2] PREDICTION OF HUMAN PHARMACOKINETICS OF EPITINIB FROM PRECLINICAL PHARMACOKINETICS BY A PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL
    Ren, Hongcan
    Gu, Yi
    Wang, Jian
    Ni, Liang
    Zhang, Weijun
    Zhang, Li
    Tang, Xianli
    Gu, Dongxia
    Zhao, Jingjing
    Xu, Xiaoyan
    Yang, Haibin
    Zhang, Weihan
    Su, Weiguo
    Sai, Yang
    DRUG METABOLISM REVIEWS, 2014, 45 : 110 - 111
  • [3] Preclinical pharmacokinetics and disposition of a novel selective VEGFR inhibitor Fruquintinib (HMPL-013) and the prediction of its human pharmacokinetics
    Yi Gu
    Jian Wang
    Ke Li
    Li Zhang
    Hongcan Ren
    Lixia Guo
    Yang Sai
    Weihan Zhang
    Weiguo Su
    Cancer Chemotherapy and Pharmacology, 2014, 74 : 95 - 115
  • [4] Preclinical pharmacokinetics and disposition of a novel selective VEGFR inhibitor Fruquintinib (HMPL-013) and the prediction of its human pharmacokinetics
    Gu, Yi
    Wang, Jian
    Li, Ke
    Zhang, Li
    Ren, Hongcan
    Guo, Lixia
    Sai, Yang
    Zhang, Weihan
    Su, Weiguo
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2014, 74 (01) : 95 - 115
  • [5] Preclinical pharmacokinetics of a novel HIV-1 attachment inhibitor BMS-378806 and prediction of its human pharmacokinetics
    Yang, Z
    Zadjura, L
    D'Arienzo, C
    Marino, A
    Santone, K
    Klunk, L
    Greene, D
    Lin, PF
    Colonno, R
    Wang, T
    Meanwell, N
    Hansel, S
    BIOPHARMACEUTICS & DRUG DISPOSITION, 2005, 26 (09) : 387 - 402
  • [6] Preclinical pharmacokinetics of the novel PI3K inhibitor GDC-0941 and prediction of its pharmacokinetics and efficacy in human
    Salphati, Laurent
    Pang, Jodie
    Plise, Emile G.
    Chou, Bilin
    Halladay, Jason S.
    Olivero, Alan G.
    Rudewicz, Patrick J.
    Tian, Qingping
    Wong, Susan
    Zhang, Xiaolin
    XENOBIOTICA, 2011, 41 (12) : 1088 - 1099
  • [7] Prediction of human pharmacokinetics based on preclinical in vitro and in vivo data
    Lavé, T
    Luttringer, O
    Zuegge, J
    Schneider, G
    Coassolo, R
    Theil, FR
    PHARMACOKINETIC CHALLENGES IN DRUG DISCOVERY, 2002, 37 : 81 - 104
  • [8] Prediction of Human Pharmacokinetics of Fomepizole from Preclinical Species Pharmacokinetics Based on Normalizing Time Course Profiles
    Jairam, Ravi Kumar
    Mallurwar, Sadanand Rangnathrao
    Sulochana, Suresh P.
    Chandrasekhar, Devaraj V.
    Todmal, Umesh
    Bhamidipati, Ravi Kanth
    Richter, Wolfgang
    Srinivas, Nuggehally R.
    Mullangi, Ramesh
    AAPS PHARMSCITECH, 2019, 20 (06)
  • [9] Prediction of Human Pharmacokinetics of Bendamustine from Preclinical Species Pharmacokinetics Based on Normalizing Time Course Profiles
    Jairam, Ravi Kumar
    Niallurwar, Sadanand Rangnathrao
    Sulochana, Suresh P.
    Chandrasekar, Devaraj, V
    Bhamidipati, Ravi Kanth
    Richter, Wolfgang
    Srinivas, Nuggehally R.
    Mullangi, Ramesh
    DRUG RESEARCH, 2019, 69 (01) : 32 - 39
  • [10] Prediction of Human Pharmacokinetics of Fomepizole from Preclinical Species Pharmacokinetics Based on Normalizing Time Course Profiles
    Ravi Kumar Jairam
    Sadanand Rangnathrao Mallurwar
    Suresh P. Sulochana
    Devaraj V. Chandrasekhar
    Umesh Todmal
    Ravi Kanth Bhamidipati
    Wolfgang Richter
    Nuggehally R. Srinivas
    Ramesh Mullangi
    AAPS PharmSciTech, 20