A Unique Model for Treating Chronic Hepatitis C in Patients With Psychiatric Disorders, Substance Abuse, and/or Housing Instability
被引:16
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作者:
Ho, Cheryl J.
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机构:
Santa Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USA
Stanford Univ, Sch Med, Stanford, CA 94305 USASanta Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USA
Ho, Cheryl J.
[1
,3
]
Preston, Charles
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机构:
Santa Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USASanta Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USA
Preston, Charles
[1
]
Fredericks, Kim
论文数: 0引用数: 0
h-index: 0
机构:
Santa Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USASanta Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USA
Fredericks, Kim
[1
]
Doorley, Sara L.
论文数: 0引用数: 0
h-index: 0
机构:
Santa Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USA
Stanford Univ, Sch Med, Stanford, CA 94305 USASanta Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USA
Doorley, Sara L.
[1
,3
]
Kramer, Richard J.
论文数: 0引用数: 0
h-index: 0
机构:
Santa Clara Valley Med Ctr, Div Gastroenterol, San Jose, CA 95128 USA
Stanford Univ, Sch Med, Stanford, CA 94305 USASanta Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USA
Kramer, Richard J.
[2
,3
]
Kwan, Lawrence
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机构:
Santa Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USASanta Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USA
Kwan, Lawrence
[1
]
Kamal, Ahmad
论文数: 0引用数: 0
h-index: 0
机构:
Santa Clara Valley Med Ctr, Div Gastroenterol, San Jose, CA 95128 USA
Stanford Univ, Sch Med, Stanford, CA 94305 USASanta Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USA
Kamal, Ahmad
[2
,3
]
机构:
[1] Santa Clara Valley Med Ctr, Dept Med, Div Primary Care, Valley Homeless Healthcare Program, San Jose, CA 95128 USA
[2] Santa Clara Valley Med Ctr, Div Gastroenterol, San Jose, CA 95128 USA
[3] Stanford Univ, Sch Med, Stanford, CA 94305 USA
Background: Individuals with psychiatric disease, substance abuse, and/or housing instability have a high prevalence of chronic hepatitis C virus (HCV) infection. However, such individuals are often excluded from treatment for HCV infection because of a perceived inability to adhere to the rigorous medication regimen required. Methods: A pilot program using a multidisciplinary group medical visit model to treat HCV infection in the aforementioned population was created. Medication adherence and virologic response rates were prospectively followed. Results: Approximately 80% of patients were adherent to their HCV infection treatment regimen, as measured by attendance at group medical visits and by medication adherence. A sustained virologic response rate of 55% among individuals with genotype 1 infection and 80% among individuals with genotype 2 or 3 infections was observed. These results compare favorably with those seen in large, randomized controlled trials. Rates of discontinuation and adverse effects were similar to those seen in other studies. Conclusions: An intensive, multidisciplinary treatment approach toward HCV infection treatment can achieve favorable results even in persons traditionally considered to be "poor treatment candidates." Programs aimed at bringing HCV infection treatment to this population are needed.
机构:
VISN 22 Network Office
Department of Psychiatry, University of California San Diego
VA Long Beach Healthcare System
Department of Psychiatry and Human Behavior, University of California IrvineVISN 22 Network Office
机构:
VISN 22 Network Off, 300 Oceangate Ave,Suite 700, Long Beach, CA 90822 USA
Univ Calif Irvine, Dept Psychiat & Human Behav, Irvine, CA 92697 USA
Univ Calif San Diego, Dept Psychiat, San Diego, CA 92093 USA
VA Long Beach Healthcare Syst, Long Beach, CA 90822 USAVISN 22 Network Off, 300 Oceangate Ave,Suite 700, Long Beach, CA 90822 USA
Hauser, Peter
Kern, Shira
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h-index: 0
机构:
VA Long Beach Healthcare Syst, Long Beach, CA 90822 USAVISN 22 Network Off, 300 Oceangate Ave,Suite 700, Long Beach, CA 90822 USA