Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease

被引：113
|
作者：
Romito, LMA
Scerrati, M
Contarino, MF
Bentivoglio, AR
Tonali, P
Albanese, A
机构：
[1] Ist Nazl Neurol Carlo Besta, I-20133 Milan, Italy
[2] Univ Cattolica Sacro Cuore, Ist Neurochirurg, Rome, Italy
[3] Univ Cattolica Sacro Cuore, Ist Neurol, Rome, Italy
来源：
NEUROLOGY | 2002年 / 58卷 / 10期
关键词：
D O I：
10.1212/WNL.58.10.1546
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Twenty-two patients with PD received bilateral implants for high frequency stimulation of the subthalamic nucleus. The patients were treated for more than 1 year (up to 36 months). At the last visit, the Unified Parkinson Disease Rating Scale (UPDRS) motor score without medication improved by 50.2% (p < 0.001) and the UPDRS activities of daily living score improved by 68.4% (p < 0.001). The most common long-lasting adverse events were hypophonia and dysarthria; transient events were increased sexuality and mania. The surgical procedure induced transient intraoperative psychosis in seven patients.
引用
收藏
页码：1546 / 1550
页数：5
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