Serum Alpha-Fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype

被引：15

作者：

Abdoul, Hendy ^{[1
]}

Mallet, Vincent ^{[2
]}

Pol, Stanislas ^{[2
]}

Fontanet, Arnaud ^{[1
]}

机构：

[1] Inst Pasteur, Unite Epidemiol Malad Emergentes, Paris, France

[2] Univ Paris 05, Hop Cochin, APHP, Unite Hepatol, INSERM U567, Paris, France

来源：

PLOS ONE | 2008年 / 3卷 / 06期

关键词：

D O I：

10.1371/journal.pone.0002391

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We examined the association between serum alpha-fetoprotein (AFP) level and sustained virological response (SVR) in 93 chronic hepatitis C patients. The SVR rate was much higher among patients with serum AFP levels below rather than above the median value (5.7 ng/ml) (58.7% and 19.2%, respectively; P < 0.0001). Serum AFP should be added to the list of factors predictive of treatment response in chronic hepatitis C.

引用

页数：4

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