The ketogenic diet in pharmacoresistant childhood epilepsy

被引:65
|
作者
Winesett, Steven Parrish [1 ]
Bessone, Stacey Kordecki [2 ]
Kossoff, Eric H. W. [3 ]
机构
[1] Univ S Florida, Johns Hopkins Univ, Johns Hopkins All Childrens Hosp, St Petersburg, FL 33701 USA
[2] Johns Hopkins All Childrens Hosp, St Petersburg, FL USA
[3] Johns Hopkins Univ Hosp, Neurol & Pediat, Ketogen Diet Ctr, Pediat Neurol Residency Program, Baltimore, MD 21287 USA
关键词
doose syndrome; epilepsy; GLUT-1; deficiency; infantile spasms; ketogenic; lennox-gastaut syndrome; low glycemic index diet; MCT diet; modified atkins diet; seizures; MYOCLONIC-ASTATIC EPILEPSY; MODIFIED ATKINS DIET; SINGLE-CENTER EXPERIENCE; GLYCEMIC-INDEX TREATMENT; ALTERNATING HEMIPLEGIA; REFRACTORY EPILEPSY; DEFICIENCY SYNDROME; DRAVET SYNDROME; EFFICACY; CHILDREN;
D O I
10.1586/14737175.2015.1044982
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Available pharmacologic treatments for seizures are limited in their efficacy. For a patient with seizures, pharmacologic treatment with available anticonvulsant medications leads to seizure control in <70% of patients. Surgical resection can lead to control in a select subset of patients but still leaves a significant number of patients with uncontrolled seizures. The ketogenic diet and related diets have proven to be useful in pharmacoresistant childhood epilepsy.
引用
收藏
页码:621 / 628
页数:8
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