Acquired immunodeficiency syndrome related Kaposi's sarcoma eroding the maxillary bone
被引:3
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作者:
Konstantinopoulos, P. A.
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Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Hematol Oncol, Boston, MA 02215 USAHarvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Hematol Oncol, Boston, MA 02215 USA
Konstantinopoulos, P. A.
[1
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Goldsztein, H.
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Univ Maryland, Med Ctr, Dept Otorhinolaryngol Head & Neck Surg, Baltimore, MD 21201 USAHarvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Hematol Oncol, Boston, MA 02215 USA
Goldsztein, H.
[2
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Dezube, B. J.
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Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Hematol Oncol, Boston, MA 02215 USAHarvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Hematol Oncol, Boston, MA 02215 USA
Dezube, B. J.
[1
]
Pantanowitz, L.
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Tufts Univ, Sch Med, Dept Pathol, Baystate Med Ctr, Springfield, MA 01199 USAHarvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Hematol Oncol, Boston, MA 02215 USA
Pantanowitz, L.
[3
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机构:
[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Hematol Oncol, Boston, MA 02215 USA
[2] Univ Maryland, Med Ctr, Dept Otorhinolaryngol Head & Neck Surg, Baltimore, MD 21201 USA
[3] Tufts Univ, Sch Med, Dept Pathol, Baystate Med Ctr, Springfield, MA 01199 USA
Backaround: Oral involvement is a common manifestation of acquired immunodeficiency syndrome related Kaposi's sarcoma, and it occurs in approximately one-third of afflicted patients. Methods: We report an unusual case of Kaposi's sarcoma of the hard palate which invaded the underlying maxillary bone. Results: The patient underwent excisional biopsy and was subsequently treated with localised radiation and systemic chemotherapy including liposomal doxorubicin. Conclusions: The presentation, differential diagnosis, radiographic appearance and management of this serious complication are discussed. Our case highlights the need for a multidisciplinary approach, consisting of ENT. oncology and infectious disease consultation, to ensure appropriate management of maxillofacial intraosseous, acquired immunodeficiency syndrome related Kaposi's sarcoma.