Acquired immunodeficiency syndrome related Kaposi's sarcoma eroding the maxillary bone

Backaround: Oral involvement is a common manifestation of acquired immunodeficiency syndrome related Kaposi's sarcoma, and it occurs in approximately one-third of afflicted patients. Methods: We report an unusual case of Kaposi's sarcoma of the hard palate which invaded the underlying maxillary bone. Results: The patient underwent excisional biopsy and was subsequently treated with localised radiation and systemic chemotherapy including liposomal doxorubicin. Conclusions: The presentation, differential diagnosis, radiographic appearance and management of this serious complication are discussed. Our case highlights the need for a multidisciplinary approach, consisting of ENT. oncology and infectious disease consultation, to ensure appropriate management of maxillofacial intraosseous, acquired immunodeficiency syndrome related Kaposi's sarcoma.