Synthesis and antibacterial activities of 4-amino-3-(1-aryl-5-methyl-1,2,3-triazol-4-yl)-5-mercapto-1,2,4-triazoles/2-amino-5-(1-aryl-5-methyl-1,2,3-triazol-4-y1)-1,3,4-thiadiazoles and their derivatives

Treatment of 4-ammo-3-(1-aryl-5-methyl-1, 2, 3-triazol-4-yl)-5-mercapto-1, 2, 4-triazoles/2-amino-5-(1-aryl-5-methyl-1, 2, 3-triaza-4-yl)-1,3,4-thiadiazoles with benzaldehyde, acetone and omega-bromoacetophenone was tested and compared. The title compounds Schiff bases, amides, imidazolo [2,1-b] -1, 3, 4-thiadiazoles and 7 H-s-triazolo [3, 4-b]-1, 3, 4-thiadiazines have been confirmed by elemental analyses, H-1 NMR, IR and MS spectra. All the compounds have also been screened for their antibacterial activities against B. subtilis, S. aureus and E. coli.