A one-pot process for the regioselective synthesis of 1,3,4-trisubstituted-1H-pyrazoles

被引：12
|
作者：
Raw, Steven A. [1 ]
Turner, Andrew T. [1 ]
机构：
[1] AstraZeneca, Proc Res & Dev, Macclesfield SK10 2NA, Cheshire, England
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 06期
关键词：
PYRAZOLE;
D O I：
10.1016/j.tetlet.2008.11.099
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
This Letter reports a facile and regioselective one-pot synthesis of 1,3,4-trisubstituted-1H-pyrazoles. It comprises a three-step telescoped sequence. which has been utilised in the production of a variety of differentially substituted pyrazoles. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：696 / 699
页数：4
相关论文
共 50 条
  • [1] Facile One-Pot Synthesis of 1,3,5-Trisubstituted Pyrazoles from α,β-Enones
    Yu, Jin
    Kim, Ko Hoon
    Moon, Hye Ran
    Kim, Jae Nyoung
    [J]. BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2014, 35 (06): : 1692 - 1696
  • [2] One-pot facile synthesis of 1,3,4-trisubstituted imidazolin-2-ones
    Cheng, YF
    Hu, YZ
    [J]. JOURNAL OF CHEMICAL RESEARCH, 2004, (04) : 292 - 293
  • [3] ONE-POT SYNTHESIS OF TRISUBSTITUTED PYRAZOLES VIA MULTICOMPONENT APPROACH
    Santhosh, P.
    Chunduru, V. S. R.
    Rao, V. Rajeswar
    [J]. CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2011, 47 (04) : 448 - 451
  • [4] One-pot synthesis of trisubstituted pyrazoles via multicomponent approach
    P. Santhosh
    V. S. R. Chunduru
    V. Rajeswar Rao
    [J]. Chemistry of Heterocyclic Compounds, 2011, 47 : 448 - 451
  • [5] REGIOSELECTIVE SYNTHESIS OF 1,3,5-TRISUBSTITUTED PYRAZOLES
    Desai, Vidya G.
    Satardekar, Pooja C.
    Polo, Sampada
    Dhumaskar, Kashinath
    [J]. SYNTHETIC COMMUNICATIONS, 2012, 42 (06) : 836 - 842
  • [6] An efficient one-pot synthesis of 1,3,5-substituted-1H-pyrazoles derivatives
    Hassanabadi, Alireza
    Hosseini-Tabatabaei, Mohammad R.
    Shahraki, Mehdi
    Anary-Abbasinejad, Mohammad
    Ghoroghchian, Saeedeh
    [J]. JOURNAL OF CHEMICAL RESEARCH, 2011, (01) : 11 - 14
  • [7] One-pot regioselective synthesis of 1,4,5-trisubstituted pyrazoles under solvent-free conditions without catalyst
    Alinezhad, Heshmatollah
    Tajbakhsh, Mahmood
    Zare, Mahboobeh
    [J]. MONATSHEFTE FUR CHEMIE, 2012, 143 (06): : 947 - 950
  • [8] One-pot regioselective synthesis of 1,4,5-trisubstituted pyrazoles under solvent-free conditions without catalyst
    Heshmatollah Alinezhad
    Mahmood Tajbakhsh
    Mahboobeh Zare
    [J]. Monatshefte für Chemie - Chemical Monthly, 2012, 143 : 947 - 950
  • [9] Three-component, one-pot reaction for the combinatorial synthesis of 1,3,4-substituted pyrazoles
    Xie, FC
    Cheng, G
    Hu, YH
    [J]. JOURNAL OF COMBINATORIAL CHEMISTRY, 2006, 8 (03): : 286 - 288
  • [10] An Efficient One-Pot Synthesis of 3,5-Disubstituted 1H-Pyrazoles
    Wu, Lei-Lei
    Ge, Yi-Cen
    He, Ting
    Zhang, Lei
    Fu, Xing-Li
    Fu, Hai-Yan
    Chen, Hua
    Li, Rui-Xiang
    [J]. SYNTHESIS-STUTTGART, 2012, 44 (10): : 1577 - 1583
12345