Immunotherapy in Nonmelanoma Skin Cancer

被引：4

作者：

Bassas Freixas, P. ^{[1
]}

Aparicio Espanol, G. ^{[1
]}

Garcia-Patos Briones, V ^{[1
]}

机构：

[1] Hosp Univ Vail dHebron, Serv Dermatol, Barcelona, Spain

来源：

ACTAS DERMO-SIFILIOGRAFICAS | 2019年 / 110卷 / 05期

关键词：

Nonmelanoma skin cancer; Immunotherapy; Programmed cell death protein 1 (PD-1); Programmed death ligand 1 (PD-L1); Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4); SQUAMOUS-CELL CARCINOMA; LONG-TERM SURVIVAL; DEATH LIGAND; IPILIMUMAB; EXPRESSION; PEMBROLIZUMAB; REGRESSION; BLOCKADE; CTLA-4; PD-L2;

D O I：

10.1016/j.ad.2018.09.013

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Immunotherapy is emerging as a new and promising treatment for a great variety of tumors, including nonmelanoma skin cancer. Checkpoint inhibitors - antibodies that block proteins that regulate the immune system - mainly target the surface protein CTLA-4 (cytotoxic T-lymphocyte-associated antigen 4) and the PD-1/PD-L1 (programmed cell death protein 1/PD-ligand 1) axis. We review the CTLA-4 and PD-1/PD-L1 pathways and current evidence supporting checkpoint inhibitor therapy in the main types of nonmelanoma skin cancer. (C) 2018 AEDV. Published by Elsevier Espana, S.L.U. All rights reserved.

引用

页码：353 / 359

页数：7

共 50 条

[31] Updates and new perspectives in nonmelanoma skin cancer therapy: highlights from 'Immunotherapy Bridge'
Ascierto, Paolo Antonio
Garbe, Claus
IMMUNOTHERAPY, 2020, 12 (03) : 167 - 174
[32] Chemoprevention of Nonmelanoma Skin Cancer
Soltani-Arabshahi, Razieh
Tristani-Firouzi, Payam
FACIAL PLASTIC SURGERY, 2013, 29 (05) : 373 - 383
[33] Anatomy of the Skin and the Pathogenesis of Nonmelanoma Skin Cancer
Losquadro, William D.
FACIAL PLASTIC SURGERY CLINICS OF NORTH AMERICA, 2017, 25 (03) : 283 - +
[34] Management of nonmelanoma Skin Cancer in 2007
Maurer, P.
MKG-CHIRURG, 2008, 1 (02): : 130 - 132
[35] Nonmelanoma Skin Cancer Part 1
Nolen, Mary E.
Beebe, Victoria R.
King, Jeanne M.
Bryn, Niki
Limaye, Karen Morin
JOURNAL OF THE DERMATOLOGY NURSES ASSOCIATION, 2011, 3 (05) : 260 - 283
[36] Therapeutic Cancer Vaccines for Nonmelanoma Skin Cancer
Shou-En Wu
Yi-Hsien Chen
Chih-Tsung Hung
Bing-Heng Yang
Current Treatment Options in Oncology, 2023, 24 : 496 - 514
[37] Cancer risk after nonmelanoma skin cancer
Bonn, D
LANCET, 1998, 352 (9131): : 885 - 885
[38] Nonmelanoma skin cancer in vitro reconstructed
Cortivo, R.
TISSUE ENGINEERING PART A, 2008, 14 (05) : 762 - 762
[39] Radiotherapy treatment for nonmelanoma skin cancer
Rong, Yi
Zuo, Li
Shang, Lu
Bazan, Jose G.
EXPERT REVIEW OF ANTICANCER THERAPY, 2015, 15 (07) : 765 - 776
[40] Therapeutic Cancer Vaccines for Nonmelanoma Skin Cancer
Wu, Shou-En
Chen, Yi-Hsien
Hung, Chih-Tsung
Yang, Bing-Heng
CURRENT TREATMENT OPTIONS IN ONCOLOGY, 2023, 24 (05) : 496 - 514

← 1 2 3 4 5 →