New insights into the role of NK cells in cancer immunotherapy

被引：26
|
作者：
Salagianni, Maria [1 ]
Baxevanis, Constantin N. [1 ]
Papamichail, Michael [1 ]
Perez, Sonia A. [1 ]
机构：
[1] St Savas Canc Hosp, Canc Immunol & Immunotherapy Ctr, Athens, Greece
来源：
ONCOIMMUNOLOGY | 2012年 / 1卷 / 02期
关键词：
NATURAL-KILLER-CELLS;
D O I：
10.4161/onci.1.2.18398
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Repetitive infusions of ex vivo expanded NK cells induced antitumor T-cell responses in a metastatic lung cancer mouse model. These were further potentiated by Treg depletion. Thus the combination of NK cell-based immunotherapy with other treatment modalities in the direction of adaptive response enhancement might promote long lasting antitumor immunity.
引用
收藏
页码：205 / 207
页数：3
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