Oxidative stress induced by continuous hepatocyte apoptosis drives liver carcinogenesis independently of regeneration and DNA methylation status

被引:0
|
作者
Hikita, Hayato [1 ]
Tatsumi, Tomohide [1 ]
Saito, Yoshinobu [1 ]
Tanaka, Satoshi [1 ]
Shimizu, Satoshi [1 ]
Li, Wei [1 ]
Sakamori, Ryotaro [1 ]
Miyagi, Takuya [1 ]
Hiramatsu, Naoki [1 ]
Takehara, Tetsuo [1 ]
机构
[1] Osaka Univ, Guraduate Sch Med, Suita, Osaka, Japan
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
1793
引用
收藏
页码:1069A / 1069A
页数:1
相关论文
共 50 条
  • [41] Oxidative Stress and Ca2+ Signals Involved on Cadmium-Induced Apoptosis in Rat Hepatocyte
    Jicang Wang
    Huali Zhu
    Xuezhong Liu
    Zongping Liu
    Biological Trace Element Research, 2014, 161 : 180 - 189
  • [42] Folic acid modulates VPO1 DNA methylation levels and alleviates oxidative stress-induced apoptosis in vivo and in vitro
    Cui, Shanshan
    Lv, Xin
    Li, Wen
    Li, Zhenshu
    Liu, Huan
    Gao, Yuxia
    Huang, Guowei
    REDOX BIOLOGY, 2018, 19 : 81 - 91
  • [43] Melatonin attenuates oxidative stress, liver damage and hepatocyte apoptosis after bile-duct ligation in rats
    Aktas, Cevat
    Kanter, Mehmet
    Erboga, Mustafa
    Mete, Rafet
    Oran, Mustafa
    TOXICOLOGY AND INDUSTRIAL HEALTH, 2014, 30 (09) : 835 - 844
  • [44] Effect of Plasma Exchange on Hepatocyte Oxidative Stress, Mitochondria Function, and Apoptosis in Patients With Acute Fatty Liver of Pregnancy
    Tang, Wanxin
    Huang, Zhongying
    Wang, Yufang
    Bo, Hong
    Fu, Ping
    ARTIFICIAL ORGANS, 2012, 36 (03) : E39 - E47
  • [45] Ethanol impaired liver regeneration is associated with increased oxidative stress and DNA damage in hepatocytes.
    Chaudhry, Rajeev
    Duan, Kevin
    Pang, Maoyin
    Wands, Jack
    de la Monte, Suzanne
    FASEB JOURNAL, 2007, 21 (05): : A188 - A188
  • [46] Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress
    Venkatachalam, Gireedhar
    Surana, Uttam
    Clement, Marie-Veronique
    NUCLEIC ACIDS RESEARCH, 2017, 45 (18) : 10564 - 10582
  • [47] Apoptosis signal-regulating kinase 1 is crucial for oxidative stress-induced but not for osmotic stress-induced hepatocyte cell death
    Taki, Kenji
    Shimozono, Rieko
    Kusano, Hajime
    Suzuki, Nobutaka
    Shinjo, Katsuhiro
    Eda, Hiroyuki
    LIFE SCIENCES, 2008, 83 (25-26) : 859 - 864
  • [48] Role of rPAF in inflammation and apoptosis in drug-induced model of liver injury. Effects of rPAF-AH in liver regeneration and oxidative stress.
    Grypioti, Agni
    Mykoniatis, Michael
    Kostopanagiotou, Georgia
    ACTA PHARMACOLOGICA SINICA, 2006, 27 : 362 - 362
  • [49] Roles of oxidative stress and endoplasmic reticulum stress in selenium deficiency-induced apoptosis in chicken liver
    Yao, Linlin
    Du, Qiang
    Yao, Haidong
    Chen, Xi
    Zhang, Ziwei
    Xu, Shiwen
    BIOMETALS, 2015, 28 (02) : 255 - 265
  • [50] Roles of oxidative stress and endoplasmic reticulum stress in selenium deficiency-induced apoptosis in chicken liver
    Linlin Yao
    Qiang Du
    Haidong Yao
    Xi Chen
    Ziwei Zhang
    Shiwen Xu
    BioMetals, 2015, 28 : 255 - 265