Sublingual immunotherapy in preschool children: an update

被引：1

作者：

Vitaliti, Giovanna ^{[1
]}

Pavone, Piero

Guglielmo, Francesco

Falsaperla, Raffaele

机构：

[1] Univ Catania, Azienda Osped Univ Policlin Vittorio Emanuele, Pediat Complex Operat Unit, Catania, Italy

来源：

EXPERT REVIEW OF CLINICAL IMMUNOLOGY | 2013年 / 9卷 / 04期

关键词：

efficacy; literature review; preschool children; safety; sublingual immunotherapy; HOUSE-DUST MITE; DOUBLE-BLIND; ALLERGIC RHINITIS; SYSTEMIC REACTIONS; IMMUNOLOGICAL MECHANISMS; SWALLOW IMMUNOTHERAPY; IN-VITRO; SAFETY; EFFICACY; HYPOSENSITIZATION;

D O I：

10.1586/ECI.13.7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Allergen immunotherapy is a subject widely debated by allergists. Currently, there are controversial discussions focused on the sublingual route. Sublingual immunotherapy (SLIT) has so far been used in Europe, Asia and Australia for the treatment of allergic respiratory diseases. The minimum age to start specific immunotherapy with inhalant allergens in children has not been clearly established, and position papers discourage its use in children younger than 5 years of age. Nevertheless, it is known that SLIT efficacy is higher when SLIT is started at an earlier age. The aim of this review is to focus on studies in preschool children evaluating SLIT safety and efficacy, in order to improve this practice at an earlier age in childhood.

引用

页码：385 / 390

页数：6

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