Novel series of pyrazolylpiperidine N-type calcium channel blockers

被引:0
|
作者
Subasinghe, Nalin L. [1 ]
Wall, Mark [1 ]
Winters, Michael P. [1 ]
Qin, Ning [1 ]
Lubin, Mary L. [1 ]
Finley, Michael F. [1 ]
Brandt, Michael R. [1 ]
Neeper, Michael [1 ]
Schneider, Craig R. [1 ]
Colburn, Raymond [1 ]
Flores, Christopher M. [1 ]
Sui, Zhihua [1 ]
机构
[1] Janssen Pharmaceut Res & Dev LLC, Spring House, PA 19477 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
103-MEDI
引用
收藏
页数:2
相关论文
共 50 条
  • [41] High-throughput screening for N-type calcium channel blockers using a scintillation proximity assay
    Zhang, Sui-Po
    Kauffman, Jack
    Yagel, Susan K.
    Codd, Ellen E.
    JOURNAL OF BIOMOLECULAR SCREENING, 2006, 11 (06) : 672 - 677
  • [42] The combined effects of N-type calcium channel blockers and morphine on Aδ versus C fiber mediated nociception
    Pirec, V
    Laurito, CE
    Lu, Y
    Yeomans, DC
    ANESTHESIA AND ANALGESIA, 2001, 92 (01): : 239 - 243
  • [43] Synthesis and biological evaluation of substituted α-methyl-3-(trifluoromethyl)benzeneethanamine derivatives as novel N-type calcium channel blockers.
    Kornberg, BE
    Nikam, SS
    Stoehr, S
    Rock, DM
    Downing, D
    Warmus, J
    Rafferty, MF
    Weber, ML
    Szoke, BG
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 219 : U48 - U48
  • [44] N-type Calcium Channel Blocker for Pain Treatment
    Mao, Jianren
    PAIN MEDICINE, 2010, 11 (02) : 153 - 153
  • [45] The role of N-type calcium channel in renal podocytes
    Liu, Ya
    Nakano, Daisuke
    Shibayama, Yuki
    Nishiyama, Akira
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2014, 124 : 126P - 126P
  • [46] N-type calcium channel blockade in diabetic nephropathy
    Fujisawa, Tomomi
    Ikegami, Hiroshi
    Noso, Shisuke
    Hiromine, Yoshihisa
    Kawabata, Yumiko
    Asano, Katsuaki
    Nojima, Koji
    Fukai, Aya
    Shindo, Nobuyasu
    Ogihara, Toshio
    JOURNAL OF HYPERTENSION, 2006, 24 : 225 - 225
  • [47] Dipyridyltriazoles: A novel series of store-operated calcium channel blockers
    Zinkand, WC
    Warawa, EJ
    Falcone, RC
    Patel, J
    Christian, EP
    BIOPHYSICAL JOURNAL, 1998, 74 (02) : A376 - A376
  • [48] Structure-activity study and analgesic efficacy of amino acid derivatives as N-type calcium channel blockers
    Seko, T
    Kato, M
    Kohno, H
    Ono, S
    Hashimura, K
    Takimizu, H
    Nakai, K
    Maegawa, H
    Katsube, N
    Toda, M
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2001, 11 (16) : 2067 - 2070
  • [49] Identification and SAR studies of PD 151307, a novel N-type calcium channel blocker
    Malone, T
    Booth, J
    Campbell, G
    Cody, W
    Geer, JJ
    He, J
    Hu, LY
    Lescosky, LJ
    Miljanich, G
    Nadasdi, L
    Rafferty, MF
    Rock, D
    Sercel, A
    Stoehr, S
    Song, YT
    Szoke, BG
    Tarczy-Hornoch, K
    Taylor, C
    Urge, L
    Vartanian, M
    Weber, M
    Yi, S
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 217 : U1191 - U1191
  • [50] PD 151307 analogs: Synthesis and biological evaluation of substituted 4-(OBz)phenylalanine derivatives as novel N-type calcium channel blockers
    Hu, LY
    Ryder, TR
    Nikam, S
    Millerman, E
    Szoke, BG
    Taylor, CP
    Rafferty, MF
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 217 : U1190 - U1190