Hollow Manganese Oxide Nanoparticles as Multifunctional Agents for Magnetic Resonance Imaging and Drug Delivery

被引：421
|
作者：
Shin, Jongmin [2 ]
Anisur, Rahman Md [2 ]
Ko, Mi Kyeong [1 ]
Im, Getcn Ho [1 ]
Lee, Jung Hee [1 ]
Lee, In Su [2 ]
机构：
[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea
[2] Kyung Hee Univ, Dept Chem & Adv Mat Sci, Gyeonggi Do 446701, South Korea
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 02期
关键词：
contrast agents; drug delivery; magnetic resonance imaging; manganese; nanoparticles; CONTRAST AGENTS; MNO NANOPARTICLES; NANOCRYSTALS; CANCER; SPHERES; CELLS;
D O I：
10.1002/anie.200802323
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
MRI jack-o'-lanterns? Hollow manganese oxide nanoparticles (HMON) show greatly improved relaxivities and drug-loading capacities compared to those with solid interiors (WMON). Their efficient cellular uptake demonstrates their potential as a bifunctional medical system that combines diagnostic imaging and targeted therapy. (Figure Presented). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：321 / 324
页数：4
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