Hollow Manganese Oxide Nanoparticles as Multifunctional Agents for Magnetic Resonance Imaging and Drug Delivery

被引：421

作者：

Shin, Jongmin ^{[2
]}

Anisur, Rahman Md ^{[2
]}

Ko, Mi Kyeong ^{[1
]}

Im, Getcn Ho ^{[1
]}

Lee, Jung Hee ^{[1
]}

Lee, In Su ^{[2
]}

机构：

[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea

[2] Kyung Hee Univ, Dept Chem & Adv Mat Sci, Gyeonggi Do 446701, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 02期

关键词：

contrast agents; drug delivery; magnetic resonance imaging; manganese; nanoparticles; CONTRAST AGENTS; MNO NANOPARTICLES; NANOCRYSTALS; CANCER; SPHERES; CELLS;

D O I：

10.1002/anie.200802323

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

MRI jack-o'-lanterns? Hollow manganese oxide nanoparticles (HMON) show greatly improved relaxivities and drug-loading capacities compared to those with solid interiors (WMON). Their efficient cellular uptake demonstrates their potential as a bifunctional medical system that combines diagnostic imaging and targeted therapy. (Figure Presented). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：321 / 324

页数：4

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