Duvelisib for Critically-Ill Patients with COVID-19 Disease: An Investigator-Initiated, Randomized, Placebo-Controlled Double-Blind Pilot Trial

被引：0

作者：

Goldsmith, Scott R. ^{[1
]}

Covut, Fahrettin ^{[1
]}

Fiala, Mark A. ^{[2
]}

Bradtke, Elizabeth ^{[1
]}

Gasanli, Ayan ^{[1
]}

Christen, Brandon ^{[1
]}

Pachter, Jonathan A. ^{[3
]}

Xiang, Zhifu ^{[1
]}

Iqbal, Zahid ^{[4
]}

Moore, Nathan ^{[5
]}

Ofoma, Uchenna ^{[4
]}

Parikh, Bijal ^{[6
]}

Dubberke, Erik ^{[7
]}

DiPersio, John F. ^{[8
]}

机构：

[1] Washington Univ, Sch Med, Dept Med, Div Oncol, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Div Hematol & Oncol, Dept Med, St Louis, MO 63110 USA

[3] Verastem, Needham, MA USA

[4] Washington Univ, Sch Med, Dept Anesthesiol, Div Crit Care, St Louis, MO 63110 USA

[5] Missouri Baptist Med Ctr, St Louis, MO USA

[6] Washington Univ, Sch Med, St Louis, MO 63110 USA

[7] Washington Univ, Sch Med, Dept Med, Div Infect Dis, St Louis, MO 63110 USA

[8] Washington Univ, Sch Med, Div Oncol, Dept Internal Med, St Louis, MO 63110 USA

来源：

BLOOD | 2022年 / 140卷

关键词：

D O I：

10.1182/blood-2022-157605

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：11185 / 11186

页数：2

共 50 条

[11] Nitazoxanide in Patients Hospitalized With COVID-19 Pneumonia: A Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial
Rocco, Patricia R. M.
Silva, Pedro L.
Cruz, Fernanda F.
Tierno, Paulo F. G. M. M.
Rabello, Eucir
Junior, Jefiton Cordeiro
Haag, Firmino
de avila, Renata E.
da Silva, Joana D. G.
Mamede, Mariana M. S.
Buchele, Konrad S.
Barbosa, Luiz C. V.
Cabral, Anna C.
Junqueira, Antonio A. F.
Araujo-Filho, Joao A.
da Costa, Lucianna A. T. J.
Alvarenga, Pedro P. M.
Moura, Alexandre S.
Carajeleascow, Ricardo
de Oliveira, Mirella C.
Silva, Roberta G. F.
Soares, Cynthia R. P.
Fernandes, Ana Paula S. M.
Fonseca, Flavio Guimaraes
Camargos, Vidyleison Neves
Reis, Julia de Souza
Franchini, Kleber G.
Luiz, Ronir R.
Morais, Sirlei
Sverdloff, Carlos
Martins, Camila Marinelli
Felix, Nathane S.
Mattos-Silva, Paula
Nogueira, Caroline M. B.
Caldeira, Dayene A. F.
Pelosi, Paolo
Lapa-e-Silva, Jose R.
[J]. FRONTIERS IN MEDICINE, 2022, 9
[12] Mavrilimumab in patients with severe COVID-19 pneumonia and systemic hyperinflammation (MASH-COVID): an investigator initiated, multicentre, double-blind, randomised, placebo-controlled trial
Cremer, Paul C.
Abbate, Antonio
Hudock, Kristin
McWilliams, Carla
Mehta, Jinesh
Chang, Steven Y.
Sheng, Calvin C.
Van Tassell, Benjamin
Bonaventura, Aldo
Vecchie, Alessandra
Carey, Brenna
Wang, Qiuqing
Wolski, Katherine E.
Rajendram, Prabalini
Duggal, Abhijit
Wang, Tisha S.
Paolini, John F.
Trapnell, Bruce C.
[J]. LANCET RHEUMATOLOGY, 2021, 3 (06): : E410 - E418
[13] Effect of melatonin on stress-induced hyperglycemia and insulin resistance in critically-ill patients: A randomized double-blind, placebo-controlled clinical trial
Naderi-Behdani, Fahimeh
Heydari, Fatemeh
Ala, Shahram
Moradi, Siavash
Abediankenari, Saeid
Asgarirad, Hossein
Khodabakhsh, Elmira
[J]. CASPIAN JOURNAL OF INTERNAL MEDICINE, 2022, 13 (01) : 51 - 60
[14] The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial
Vermeersch, Kristina
Gabrovska, Maria
Deslypere, Griet
Demedts, Ingel K.
Slabbynck, Hans
Aumann, Joseph
Ninane, Vincent
Verleden, Geert M.
Troosters, Thierry
Bogaerts, Kris
Brusselle, Guy G.
Janssens, Wim
[J]. INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2016, 11 : 687 - 696
[15] Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized, double-blind, placebo-controlled trial
Julio Vallejos
Rodrigo Zoni
María Bangher
Silvina Villamandos
Angelina Bobadilla
Fabian Plano
Claudia Campias
Evangelina Chaparro Campias
Maria Fernanda Medina
Fernando Achinelli
Hector Andres Guglielmone
Jorge Ojeda
Diego Farizano Salazar
Gerardo Andino
Pablo Kawerin
Silvana Dellamea
Antonia Cristina Aquino
Victor Flores
Carolina N. Martemucci
Silvina Maria Martinez
Juan Emanuel Segovia
Paola Itati Reynoso
Noelia Carolina Sosa
Mariana Elizabeth Robledo
Joaquina Maria Guarrochena
Maria Mercedes Vernengo
Natalia Ruiz Diaz
Elba Meza
María Gabriela Aguirre
[J]. BMC Infectious Diseases, 21
[16] Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized, double-blind, placebo-controlled trial
Vallejos, Julio
Zoni, Rodrigo
Bangher, Maria
Villamandos, Silvina
Bobadilla, Angelina
Plano, Fabian
Campias, Claudia
Chaparro Campias, Evangelina
Fernanda Medina, Maria
Achinelli, Fernando
Andres Guglielmone, Hector
Ojeda, Jorge
Farizano Salazar, Diego
Andino, Gerardo
Kawerin, Pablo
Dellamea, Silvana
Cristina Aquino, Antonia
Flores, Victor
Martemucci, Carolina N.
Maria Martinez, Silvina
Emanuel Segovia, Juan
Itati Reynoso, Paola
Carolina Sosa, Noelia
Elizabeth Robledo, Mariana
Maria Guarrochena, Joaquina
Mercedes Vernengo, Maria
Ruiz Diaz, Natalia
Meza, Elba
Gabriela Aguirre, Maria
[J]. BMC INFECTIOUS DISEASES, 2021, 21 (01)
[17] Effects of supplementation with curcuminoids on serum adipokines in critically ill patients: a randomized double-blind placebo-controlled trial
Shadnoush, Mahdi
Zahedi, Hoda
Norouzy, Abdolreza
Sahebkar, Amirhossein
Sadeghi, Omid
Najafi, Atabak
Hosseini, Saeed
Qorbani, Mostafa
Ahmadi, Arezoo
Ardehali, Seyed Hossein
Hosseinzadeh-Attar, Mohammad Javad
[J]. PHYTOTHERAPY RESEARCH, 2020, 34 (12) : 3180 - 3188
[18] Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator-Initiated, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial
Khanna, Dinesh
Spino, Cathie
Johnson, Sindhu
Chung, Lorinda
Whitfield, Michael L.
Denton, Christopher P.
Berrocal, Veronica
Franks, Jennifer
Mehta, Bhavan
Molitor, Jerry
Steen, Virginia D.
Lafyatis, Robert
Simms, Robert W.
Gill, Anna
Kafaja, Suzanne
Frech, Tracy M.
Hsu, Vivien
Domsic, Robyn T.
Pope, Janet E.
Gordon, Jessica K.
Mayes, Maureen D.
Schiopu, Elena
Young, Amber
Sandorfi, Nora
Park, Jane
Hant, Faye N.
Bernstein, Elana J.
Chatterjee, Soumya
Castelino, Flavia, V
Ajam, Ali
Wang, Yue
Wood, Tammara
Allanore, Yannick
Matucci-Cerinic, Marco
Distler, Oliver
Singer, Ora
Bush, Erica
Fox, David A.
Furst, Daniel E.
[J]. ARTHRITIS & RHEUMATOLOGY, 2020, 72 (01) : 125 - 136
[19] Ramipril for the Treatment of COVID-19: RAMIC, a Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Huang, Daniel Q.
Ajmera, Veeral
Tomaszewski, Christian
LaFree, Andrew
Bettencourt, Ricki
Thompson, Wesley K.
Smith, Davey M.
Malhotra, Atul
Mehta, Ravindra L.
Tolia, Vaishal
Yin, Jeffrey
Insel, Paul A.
Leachman, Stone
Jung, Jinho
Collier, Summer
Richards, Lisa
Woods, Kristin
Amangurbanova, Maral
Bhatt, Archana
Zhang, Xinlian
Penciu, Oana M.
Zarich, Stuart
Retta, Tamrat
Harkins, Michelle S.
Teixeira, J. Pedro
Chinnock, Brian
Utay, Netanya S.
Lake, Jordan E.
Loomba, Rohit
[J]. ADVANCES IN THERAPY, 2023, 40 (11) : 4805 - 4816
[20] Effect of a multispecies probiotic on inflammatory markers in critically ill patients: A randomized, double-blind, placebo-controlled trial
Sanaie, Sarvin
Ebrahimi-Mameghani, Mehrangiz
Hamishehkar, Hadi
Mojtahedzadeh, Mojtaba
Mahmoodpoor, Ata
[J]. JOURNAL OF RESEARCH IN MEDICAL SCIENCES, 2014, 19 (09): : 827 - 833

← 1 2 3 4 5 →