Effects of Platelet-rich Plasma Injection on Adhesive Capsulitis: An Interventional Case Series

The aim of this case series was to present the effectiveness of platelet-rich plasma (PRP) on pain, range of motion (ROM), and functionality in patients with frozen shoulder and chronic shoulder pain. The study included 9 patients aged 18-75 years who had shoulder pain for at least 3 months with 50% limited ROM in at least one direction and Visual Analog Scale (VAS) score > 5. Under sonography guidance, PRP injection was performed into the glenohumeral joint at baseline and on week 2. Concurrently, proprioceptive neuromuscular facilitation stretching and Codman exercises were given to all patients. Significant improvements were detected in VAS scores on weeks 2, 6, and 12 when compared with baseline (p<0.05) and Shoulder Pain and Disability Index scores in all time points when compared with baseline (p<0.05). There was a significant improvement in active and passive ROMs on weeks 2, 6, and 12 when compared with baseline (p<0.05). Treatment of adhesive capsulitis with PRP may be an alternative treatment method for patients.