New alpha-pyrone-containing metabolites from a marine-derived actinomycete

被引：71
|
作者：
Sitachitta, N [1 ]
Gadepalli, M [1 ]
Davidson, BS [1 ]
机构：
[1] UNIV HAWAII, DEPT CHEM, HONOLULU, HI 96822 USA
来源：
TETRAHEDRON | 1996年 / 52卷 / 24期
关键词：
D O I：
10.1016/0040-4020(96)00391-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Four new alpha-pyrone-containing metabolites, wailupemycins A-C (1-3) and 3-epi-5-deoxyenterocin (4), were isolated together with known compounds enterocin (6) and 5-deoxyenterocin (5) from a Streptomyces sp. cultured from shallow water marine sediments. The structures of the new compounds were determined through the interpretation of spectral data. Compound 1 exhibited antimicrobial activity towards the Gram-negative bacterium Escherichia coli, while compound 4 inhibited the growth of Staphylococcus aureus. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码：8073 / 8080
页数：8
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