HLA-B27 and HLA-B73 polymorphism and its role on antigenicity, peptide presentation, and disease susceptibility

被引：6
|
作者：
DeCastro, JAL
机构：
来源：
CLINICAL RHEUMATOLOGY | 1996年 / 15卷
关键词：
HLA-B27; HLA-B73; spondyloarthropathies; antigen presentation; T-cell recognition;
D O I：
10.1007/BF03342650
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Current ideas on the structure, evolution, and disease association of HLA-B27 antigens are presented, with emphasis on the effect of HLA-B27 polymorphism on T-cell recognition and antigen-presenting properties of these molecules. The molecular relationship between HLA-B27 and HLA-B73, and its implications for a putative pathogenetic role of the later antigen are discussed.
引用
收藏
页码：67 / 71
页数：5
相关论文
共 50 条
  • [41] ANTIGENIC CHARACTERISTICS AND CDNA SEQUENCES OF HLA-B73
    HOFFMANN, HJ
    KRISTENSEN, TJ
    JENSEN, TG
    GRAUGAARD, B
    LAMM, LU
    EUROPEAN JOURNAL OF IMMUNOGENETICS, 1995, 22 (03): : 231 - 240
  • [42] HLA-B27:: a registry of constitutive peptide ligands
    de Castro, JAL
    Alvarez, I
    Marcilla, M
    Paradela, A
    Ramos, M
    Sesma, L
    Vázquez, M
    TISSUE ANTIGENS, 2004, 63 (05): : 424 - 445
  • [43] ASSOCIATION OF WHIPPLES DISEASE WITH HLA-B27
    FEURLE, GE
    LANCET, 1985, 1 (8441): : 1336 - 1336
  • [44] Misfolding of HLA-B27 as a result of its B pocket suggests a novel mechanism for its role in susceptibility to spondyloarthropathies
    Mear, JP
    Schreiber, KL
    Münz, C
    Zhu, XM
    Stevanovic, S
    Rammensee, HG
    Rowland-Jones, SL
    Colbert, RA
    JOURNAL OF IMMUNOLOGY, 1999, 163 (12): : 6665 - 6670
  • [45] HLA-B27 TYPING
    KAPLAN, H
    ANNALS OF INTERNAL MEDICINE, 1980, 92 (06) : 871 - 872
  • [46] THE BIOLOGY OF HLA-B27
    Colbert, R. A.
    Layh-Schmitt, G.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2012, 30 (04) : 599 - 599
  • [47] HLA-B27 and bacteria
    Uksila, J
    Toivanen, P
    CLINICAL RHEUMATOLOGY, 1996, 15 : 44 - 47
  • [48] HLA-B27 IN RHEUMATOLOGY
    WELFLING, J
    REVUE DU PRATICIEN, 1977, 27 (56): : 3923 - 3925
  • [49] DYSFUNCTION OF HLA-B27
    IVANYI, P
    SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 1990, : 51 - 69
  • [50] HLA-B27 SUBTYPES
    MACLEAN, IL
    ARCHER, JR
    WHELAN, MA
    LANCET, 1991, 337 (8746): : 927 - 927
12345