Sickle Cell Beta Thalassemia: A Rare Entity

Introduction: Haemoglobinopathies are the disorders which affect the structure of hemoglobin. Most common hemoglobinopathies are sickle cell disorders and thalassemia. Sickle cell disorders are genetic disorders characterized by the predominance of hemoglobin S whereas thalassemia is the disorder of hemoglobin synthesis with decreased production of globin chains of hemoglobin molecules. Case report: We present a case of a rare hereditary disease in a 19-year-old female patient with both sickle cell and beta thalassemia traits along with the clinical, radiological manifestations, diagnosis, management, and dental considerations. Conclusion: Oral physicians and oral pathologists should be vigilant enough to identify any hemoglobinopathy, with adequate radiological and hematological investigations, although it has a rare occurrence. If diagnosed, a multidisciplinary approach involving dental surgeon, and orthodontist is mandatory for these patients