Do Decreased CEP17 Signals Indicate the Presence of "Monosomy" in Breast Cancer? A Study of HER2 Gene Status and HER2 Immunohistochemistry.

被引:0
|
作者
Tse, C. H. [1 ]
Hwang, H. C. [1 ]
Goldstein, L. C. [1 ]
Kandalaft, P. L. [1 ]
Duesterhoeft, S. M. [1 ]
Kussick, S. L. [1 ]
Gown, A. M. [1 ]
机构
[1] PhenoPath Labs, Seattle, WA USA
关键词
D O I
10.1158/0008-5472.SABCS11-P4-09-04
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P4-09-04
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Breast Carcinomas with Equivocal HER2/Neu Amplication: Morphologic Features, CEP17 Polysomy and HER2 Genetic Heterogeneity
    Astvatsaturyan, K.
    Bose, S.
    MODERN PATHOLOGY, 2012, 25 : 24A - 25A
  • [22] Breast Carcinomas with Equivocal HER2/Neu Amplification: Morphologic Features, CEP17 Polysomy and HER2 Genetic Heterogeneity
    Astvatsaturyan, K.
    Bose, S.
    LABORATORY INVESTIGATION, 2012, 92 : 24A - 25A
  • [23] Clinicopathologic Features of Breast Cancers with HER2/CEP17 Ratio <2, HER2 Copy Number ≥4 and <6 Signals/Cell
    Xu, Jin
    Brogi, Edi
    Ventura, Katia
    Ross, Dara
    Dang, Chau
    Robson, Mark
    Norton, Larry
    Morrow, Monica
    Wen, Hannah
    MODERN PATHOLOGY, 2019, 32
  • [24] Clinicopathologic Features of Breast Cancers with HER2/CEP17 Ratio <2, HER2 Copy Number ≥4 and <6 Signals/Cell
    Xu, Jin
    Brogi, Edi
    Ventura, Katia
    Ross, Dara
    Dang, Chau
    Robson, Mark
    Norton, Larry
    Morrow, Monica
    Wen, Hannah
    LABORATORY INVESTIGATION, 2019, 99
  • [25] Impact of the Change of the Criteria for HER2 Immunohistochemistry Interpretation on HER2 Status in Breast Cancer
    Harada, Shuko
    Shen, Dejun
    Wei, Shi
    MODERN PATHOLOGY, 2016, 29 : 44A - 44A
  • [26] Impact of the Change of the Criteria for HER2 Immunohistochemistry Interpretation on HER2 Status in Breast Cancer
    Harada, Shuko
    Shen, Dejun
    Wei, Shi
    LABORATORY INVESTIGATION, 2016, 96 : 44A - 44A
  • [27] Breast Cancer With a HER2 IHC2+and FISH HER2/CEP17 Ratio ≥2.0 and an Average HER2 Gene Copy Number <4.0 per Tumor Cell: HER2 mRNA Overexpression Is a Rare Event
    Liu, Yuanyuan
    Wu, Shafei
    Shi, Xiaohua
    Mao, Feng
    Zeng, Xuan
    FRONTIERS IN ONCOLOGY, 2020, 10
  • [28] HER2 status in gastric/gastro-oesophageal junctional cancers: should determination of gene amplification by SISH use HER2 copy number or HER2: CEP17 ratio?
    Kumarasinghe, Marian Priyanthi
    de Boer, Willem Bastiaan
    Khor, Tze Sheng
    Ooi, Esther M.
    Jene, Nic
    Jayasinghe, Sureshini
    Fox, Stephen B.
    PATHOLOGY, 2014, 46 (03) : 184 - 187
  • [29] HER2 Testing by FISH: Discordance between HER2 Signals Per Cell and HER2:CEP 17 Ratio
    Dintzis, S. M.
    Allison, K. H.
    Schmidt, R. A.
    CANCER RESEARCH, 2010, 70
  • [30] Prognostic value of HER2/CEP17 ratio in HER2-positive early breast cancer by FISH testing
    Zheng, F.
    Du, F.
    Yuan, P.
    ANNALS OF ONCOLOGY, 2022, 33 : S155 - S155