driftsel: an R package for detecting signals of natural selection in quantitative traits

被引：43
|
作者：
Karhunen, M. [1 ]
Merila, J. [1 ]
Leinonen, T. [1 ]
Cano, J. M. [2 ]
Ovaskainen, O. [1 ]
机构：
[1] Univ Helsinki, Dept Biosci, FI-00014 Helsinki, Finland
[2] Univ Oviedo, Res Unit Biodivers UO CSIC PA, Oviedo 33600, Spain
来源：
MOLECULAR ECOLOGY RESOURCES | 2013年 / 13卷 / 04期
基金：
芬兰科学院; 欧洲研究理事会;
关键词：
G matrix; natural selection; neutrality test; random genetic drift; G-MATRIX; GENETIC DIFFERENTIATION; Q(ST)-F-ST COMPARISONS; STABILIZING SELECTION; F-ST; EVOLUTION; DIVERGENCE; MODELS; STICKLEBACKS; NEUTRALITY;
D O I：
10.1111/1755-0998.12111
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Approaches and tools to differentiate between natural selection and genetic drift as causes of population differentiation are of frequent demand in evolutionary biology. Based on the approach of Ovaskainen etal. (2011), we have developed an R package (driftsel) that can be used to differentiate between stabilizing selection, diversifying selection and random genetic drift as causes of population differentiation in quantitative traits when neutral marker and quantitative genetic data are available. Apart from illustrating the use of this method and the interpretation of results using simulated data, we apply the package on data from three-spined sticklebacks (Gasterosteus aculeatus) to highlight its virtues. driftsel can also be used to perform usual quantitative genetic analyses in common-garden study designs.
引用
收藏
页码：746 / 754
页数：9
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