Discovery and biological evaluation of a novel, potent and selective series of ACC2 inhibitors

被引：0

作者：

Gu, Yu Gui ^{[1
]}

Weitzberg, Moshe ^{[1
]}

Clark, Richard F. ^{[1
]}

Xu, Xiangdong ^{[1
]}

Li, Qun ^{[1
]}

Zhang, Tianyuan ^{[1
]}

Hansen, T. Matthew ^{[1
]}

Keyes, Robert F. ^{[1
]}

Liu, Gang ^{[1
]}

Xin, Zhili ^{[1
]}

Wang, Xiaojun ^{[1
]}

Wang, Rongqi ^{[1
]}

McNally, Teresa ^{[1
]}

Zinker, Bradley A. ^{[1
]}

Dickinson, Bob W. ^{[1
]}

Lubbers, Nathan L. ^{[1
]}

Yang, Yi ^{[1
]}

Beno, David W. A. ^{[1
]}

Widomski, Deborah L. ^{[1
]}

Waring, Jeffrey F. ^{[1
]}

Carroll, Sherry L. ^{[1
]}

Healan-Greenberg, Christine H. ^{[1
]}

Blomme, Eric A. ^{[1
]}

Frevert, Ernst U. ^{[1
]}

Beutel, Bruce A. ^{[1
]}

Sham, Hing L. ^{[1
]}

Camp, Heidi S. ^{[1
]}

机构：

[1] Abbott Labs, Global Pharmaceut Res & Dev, Metab Dis Res, Abbott Pk, IL 60064 USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 233卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

227-MEDI

引用

页码：614 / 614

页数：1

共 50 条

[41] Discovery a series of novel inhibitors of human dihydroorotate dehydrogenase: Biological activity evaluation and molecular docking
Ren, Xiaoli
Liu, Xiaoyong
Hua, Miao
Dai, Yan
Ren, Xiaoping
Sui, Chaoya
Li, Xiangbi
Jiang, Zhiyong
Tian, Min
Yang, Bing
CHEMICAL BIOLOGY & DRUG DESIGN, 2024, 103 (01)
[42] Discovery and characterization of novel, potent, and selective hypoxia-inducible factor (HIF)-2α inhibitors
Lawson, K.
Gauthier, K. Sivick
Piovesan, D.
Fournier, J.
Rosen, B.
Maliyan, A.
Beatty, J.
Jin, L.
Leleti, M.
Ginn, E.
Udyavar, A.
Ada, C.
Au, J.
Meleza, C.
Zhao, S.
Young, S.
Walters, M.
Powers, J.
EUROPEAN JOURNAL OF CANCER, 2020, 138 : S16 - S16
[43] Discovery of novel macrocyclic derivatives as potent and selective cyclin-dependent kinase 2 inhibitors
Niu, Pengpeng
Tao, Yanxin
Meng, Qingyuan
Huang, Yixing
Li, Shan
Ding, Ke
Ma, Dawei
Ye, Zu
Fan, Mengyang
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 104
[44] Structure-based discovery and biological evaluation of novel selective TRAF6 inhibitors
Zhang, Shuxing
Du-Cuny, Lei
Darnay, Bryant
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237
[45] Arylaminoethyl carbamates as a novel series of potent and selective cathepsin S inhibitors
Tully, David C.
Liu, Hong
Chatterjee, Arnab K.
Alper, Phil B.
Williams, Jennifer A.
Roberts, Michael J.
Mutnick, Daniel
Woodmansee, David H.
Hollenbeck, Thomas
Gordon, Perry
Chang, Jonathan
Tuntland, Tove
Tumanut, Christine
Li, Jun
Harris, Jennifer L.
Karanewsky, Donald S.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (19) : 5107 - 5111
[46] Synthesis and biological evaluation of geniposide derivatives as potent and selective PTPlB inhibitors
Lei, Shuwen
Zhang, Dongdong
Qi, Yunyue
Chowdhury, Sharmin Reza
Sun, Ran
Wang, Juntao
Du, Yi
Fu, Lei
Jiang, Faqin
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 205
[47] Discovery of a novel sulfonamide-pyrazolopiperidine series as potent and Efficacious γ-Secretase Inhibitors
Ye, Xiaocong M.
Konradi, Andrei W.
Smith, Jenifer
Xu, Ying-Zi
Dressen, Darren
Garofalo, Albert W.
Marugg, Jennifer
Sham, Hing L.
Truong, Anh P.
Jagodzinski, Jacek
Pleiss, Michael
Zhang, Hongbin
Goldbach, Erich
Sauer, John-Michael
Brigham, Elizabeth
Bova, Michael
Basi, Guriqbal S.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (07) : 2195 - 2199
[48] Discovery of novel, potent γ-secretase inhibitors
Zhao, Zhiqiang
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
[49] Design, synthesis and biological evaluation of novel pyrazolo-pyrimidin-amines as potent and selective BTK inhibitors
Joshi, Darshan
Bahekar, Rajesh
Soman, Shubhangi
Jadav, Pradip
Patel, Dipam
Goswami, Amitgiri
Pethani, Jignesh
Kumar, Jeevan
Patel, Jitendra
Sundar, Rajesh
Goswami, Poonamgiri
Goshdastidar, Krishnarup
Patel, Hoshang
Patel, Ankit
Bandyopadhyay, Debdutta
Chattarjee, Abhijit
Sharma, Manoranjan
Jain, Mukul
Desai, Ranjit
BIOORGANIC CHEMISTRY, 2023, 130
[50] Discovery of Potent and Selective Covalent Inhibitors of JNK
Zhang, Tinghu
Inesta-Vaquera, Francisco
Niepel, Mario
Zhang, Jianming
Ficarro, Scott B.
Machleidt, Thomas
Xie, Ting
Marto, Jarrod A.
Kim, NamDoo
Sim, Taebo
Laughlin, John D.
Park, Hajeung
LoGrasso, Philip V.
Patricelli, Matt
Nomanbhoy, Tyzoon K.
Sorger, Peter K.
Alessi, Dario R.
Gray, Nathanael S.
CHEMISTRY & BIOLOGY, 2012, 19 (01): : 140 - 154

← 1 2 3 4 5 →