A Convenient Synthesis of Highly Substituted 3-N,N-Dialkylamino-1,2,4-triazoles

被引：16

作者：

Batchelor, David V. ^{[1
]}

Beal, David M. ^{[1
]}

Brown, T. Bruce ^{[1
]}

Ellis, David ^{[1
]}

Gordon, David W. ^{[1
]}

Johnson, Patrick S. ^{[1
]}

Mason, Helen J. ^{[1
]}

Ralph, Michael J. ^{[1
]}

Underwood, Toby J. ^{[1
]}

Wheeler, Simon ^{[1
]}

机构：

[1] Pfizer Global Res & Dev, Sandwich Chem, Sandwich CT13 9NJ, Kent, England

来源：

SYNLETT | 2008年 / 16期

关键词：

heterocycles; cyclisations; sulfur; medicinal chemistry; drugs;

D O I：

10.1055/s-2008-1078208

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title compounds are prepared from S-methylisothioureas and acyl hydrazides in moderate to good yields. The reaction is characterized by relatively mild conditions and very broad functional group tolerance.

引用

页码：2421 / 2424

页数：4

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